C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: serine/arginine-rich splicing factor 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000161547 SRSF2 9606 - 17:76734115-76737374 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000358156 SRSF2-007 76736405-76737331 protein_coding
  ENST00000359995 SRSF2-001 76734119-76737374 protein_coding
  ENST00000392485 SRSF2-003 76734115-76737333 protein_coding
  ENST00000452355 SRSF2-005 76734252-76737331 nonsense_mediated_decay
  ENST00000508921 SRSF2-002 76734577-76737331 protein_coding
  ENST00000582449 SRSF2-006 76734147-76736555 retained_intron
  ENST00000583836 SRSF2-008 76736380-76737331 protein_coding
  ENST00000585202 SRSF2-004 76734123-76737308 nonsense_mediated_decay
  ENST00000586778 SRSF2-016 76734163-76735661 retained_intron
  ENST00000589919 SRSF2-017 76734303-76736008 retained_intron
  ENST00000592676 SRSF2-015 76735137-76736154 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000359995ENST00000392485ENST00000452355ENST00000508921ENST00000582449ENST00000585202ENST00000586778
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000359995 21.216±0.00 N/A 14.545±0.00 24.431±0.00 14.282±0.00 11.855±0.00 24.241±0.00 19.581±0.00 21.124±0.00 4.578±0.00 53.115±19.28 N/A N/A
ENST00000392485 N/A N/A 2.678±0.00 3.789±0.00 2.493±0.00 N/A N/A 3.929±0.00 N/A N/A 8.523±3.88 N/A 14.226±0.00
ENST00000452355 N/A N/A N/A N/A N/A N/A N/A N/A 54.234±0.00 N/A N/A N/A N/A
ENST00000508921 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 34.373±0.00 27.048±0.00 33.098±0.00
ENST00000582449 14.287±0.00 N/A 14.487±9.46 15.693±0.00 6.756±2.42 16.529±0.00 13.704±7.99 14.569±0.00 22.317±0.00 6.502±1.49 15.403±10.71 N/A N/A
ENST00000585202 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 33.945±0.00 N/A
ENST00000586778 N/A 5.821±0.00 6.411±0.00 6.945±0.00 8.352±0.00 N/A 11.922±8.11 N/A 8.821±0.00 6.953±0.00 21.374±10.77 N/A 32.807±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003KE CIL_0003KE_0002 CGP 17:76732978-76738522
CIL_0003U9 CIL_0003U9_0002 CGP 17:76734115-76781449

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0000398 TAS mRNA splicing, via spliceosome
GO:0003676 IEA nucleic acid binding
GO:0003714 NAS transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005681 IEA spliceosomal complex
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0006369 TAS termination of RNA polymerase II transcription
GO:0006397 TAS mRNA processing
GO:0006406 TAS mRNA export from nucleus
GO:0008380 TAS RNA splicing
GO:0010467 TAS gene expression
GO:0016607 IDA nuclear speck
GO:0031124 TAS mRNA 3'-end processing
GO:0044822 IDA poly(A) RNA binding
GO:0070062 IDA extracellular vesicular exosome
GO:2001141 NAS regulation of RNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000010906 srsf2b serine/arginine-rich splicing factor 2b protein_coding Danio_rerio
ENSDARG00000057484 srsf2a serine/arginine-rich splicing factor 2a protein_coding Danio_rerio
ENSMUSG00000034120 Srsf2 serine/arginine-rich splicing factor 2 protein_coding Mus_musculus

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