C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: chemokine (C-X-C motif) ligand 16
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000161921 CXCL16 9606 - 17:4733526-4739922 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000293778 CXCL16-001 4733526-4739819 protein_coding
  ENST00000573123 CXCL16-004 4735367-4739145 protein_coding
  ENST00000574412 CXCL16-002 4734286-4739922 protein_coding
  ENST00000575168 CXCL16-005 4734583-4738539 retained_intron
  ENST00000576153 CXCL16-003 4733575-4736380 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000293778ENST00000573123ENST00000574412ENST00000575168ENST00000576153
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000293778 30.555±0.00 14.866±0.00 1.497±0.00 4.622±3.87 19.492±0.00 6.146±0.00 1.414±1.27 8.078±5.10 8.486±7.15 35.078±33.45 1.293±0.00 10.482±4.23 13.224±2.66 17.130±0.16
ENST00000573123 N/A N/A N/A N/A N/A 1.389±0.00 N/A N/A 1.403±0.00 N/A N/A N/A N/A N/A
ENST00000574412 N/A N/A N/A N/A 1.552±0.00 N/A N/A 1.250±0.00 N/A 1.166±0.00 N/A 2.855±2.05 N/A 21.886±1.94
ENST00000575168 N/A N/A N/A N/A 1.950±0.00 1.010±0.00 0.268±0.00 3.552±0.00 N/A 7.056±0.00 N/A N/A N/A 38.340±8.24
ENST00000576153 N/A N/A N/A 3.736±0.00 N/A 1.912±0.00 N/A N/A N/A N/A N/A 7.876±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000106 CIL_000106_0001 CGP 17:4710489-4733610
CIL_0001RD CIL_0001RD_0001 CGP 17:4731428-4739922
CIL_0001RE CIL_0001RE_0001 CGP 17:4733526-4746119

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005041 ISS low-density lipoprotein receptor activity
GO:0005044 TAS scavenger receptor activity
GO:0005576 TAS extracellular region
GO:0005615 IDA extracellular space
GO:0005886 IEA plasma membrane
GO:0006898 IEA:NAS receptor-mediated endocytosis
GO:0006935 NAS chemotaxis
GO:0008009 ISS chemokine activity
GO:0010818 IEA T cell chemotaxis
GO:0016020 TAS membrane
GO:0016021 NAS integral component of membrane
GO:0030307 IEA:IMP positive regulation of cell growth
GO:0030335 IEA:IMP positive regulation of cell migration
GO:0034097 IDA response to cytokine
GO:0034341 IEA:IDA response to interferon-gamma
GO:0034612 IEA:IDA response to tumor necrosis factor
GO:0048247 IEA lymphocyte chemotaxis
GO:0071222 IEA cellular response to lipopolysaccharide

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000018920 Cxcl16 chemokine (C-X-C motif) ligand 16 protein_coding Mus_musculus

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