C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: HECT domain containing E3 ubiquitin protein ligase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000165338 HECTD2 9606 + 10:91410285-91514829 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000298068 HECTD2-005 91410345-91514761 protein_coding
  ENST00000371667 HECTD2-003 91484108-91514829 protein_coding
  ENST00000371681 HECTD2-001 91410344-91463664 protein_coding
  ENST00000446394 HECTD2-201 91410285-91514826 protein_coding
  ENST00000498446 HECTD2-002 91484090-91489981 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000298068ENST00000371667ENST00000371681ENST00000446394ENST00000498446
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000298068 1.008±0.00 0.916±0.00 N/A 1.459±0.76 0.892±0.07 0.931±0.65 0.449±0.06 2.027±0.00 2.786±2.48 0.929±0.03 0.763±0.00 1.765±1.19 0.594±0.06 2.153±0.67
ENST00000371667 N/A N/A 0.138±0.00 0.700±0.00 N/A N/A N/A N/A N/A 0.717±0.00 N/A N/A N/A N/A
ENST00000371681 N/A N/A N/A 0.848±0.00 N/A N/A 0.200±0.00 N/A N/A 0.582±0.00 N/A 0.523±0.27 0.314±0.02 0.819±0.00
ENST00000446394 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.513±0.00 N/A N/A
ENST00000498446 N/A N/A 0.197±0.00 N/A N/A 0.320±0.00 0.083±0.00 0.227±0.00 2.365±0.00 0.993±0.00 N/A 0.677±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00018O CIL_00018O_0001 CGP 10:91163012-91514829
CIL_0008L8 CIL_0008L8_0001 VISTA 10:91288732-91891966
CIL_00018N CIL_00018N_0001 CGP 10:91410285-91633054

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004842 IEA:IBA ubiquitin-protein transferase activity
GO:0005634 IBA nucleus
GO:0005737 IBA cytoplasm
GO:0016567 IEA protein ubiquitination
GO:0016874 IEA ligase activity
GO:0042787 IBA protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000061194 hectd2 HECT domain containing 2 protein_coding Danio_rerio
ENSMUSG00000041180 Hectd2 HECT domain containing 2 protein_coding Mus_musculus

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