C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: general transcription factor IIA, 1, 19/37kDa
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000165417 GTF2A1 9606 - 14:81175452-81221377 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000298173 GTF2A1-004 81180178-81220952 nonsense_mediated_decay
  ENST00000434192 GTF2A1-003 81180209-81221231 protein_coding
  ENST00000553612 GTF2A1-001 81175452-81220922 protein_coding
  ENST00000556268 GTF2A1-002 81197227-81221377 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000298173ENST00000434192ENST00000553612
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000298173 N/A N/A 1.027±0.00 N/A N/A N/A N/A N/A 2.188±0.00 N/A N/A N/A N/A 4.100±0.00
ENST00000434192 N/A N/A N/A N/A 3.084±0.00 N/A N/A N/A N/A N/A N/A N/A 2.046±0.00 7.898±0.00
ENST00000553612 8.794±0.00 2.495±0.00 2.270±0.00 6.107±1.13 3.853±0.45 2.380±0.06 1.969±0.48 3.010±0.22 3.573±1.18 3.121±0.83 7.264±0.00 3.042±1.59 2.908±0.94 7.428±0.66

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004TT CIL_0004TT_0001 CGP 14:80954989-81221377
CIL_00087I CIL_00087I_0001 VISTA 14:81013259-81617678
CIL_0004TS CIL_0004TS_0001 CGP 14:81175452-81436465

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 IDA DNA binding
GO:0003713 TAS transcription coactivator activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005672 IEA transcription factor TFIIA complex
GO:0005737 IDA cytoplasm
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0006367 IEA transcription initiation from RNA polymerase II promoter
GO:0006368 TAS transcription elongation from RNA polymerase II promoter
GO:0008134 IPI transcription factor binding
GO:0010467 TAS gene expression
GO:0016032 TAS viral process
GO:0017025 IPI TBP-class protein binding
GO:0046982 IPI protein heterodimerization activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000011000 gtf2a1 general transcription factor IIA, 1 protein_coding Danio_rerio
ENSMUSG00000020962 Gtf2a1 general transcription factor II A, 1 protein_coding Mus_musculus
ENSMUSG00000094374 Gm5435 predicted gene 5435 protein_coding Mus_musculus

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