C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Rho guanine nucleotide exchange factor (GEF) 40
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000165801 ARHGEF40 9606 + 14:21070270-21090240 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000298694 ARHGEF40-001 21070270-21090240 protein_coding
  ENST00000553709 ARHGEF40-003 21070317-21089545 nonsense_mediated_decay
  ENST00000554514 ARHGEF40-006 21080897-21089545 retained_intron
  ENST00000555038 ARHGEF40-004 21070273-21075553 protein_coding
  ENST00000555052 ARHGEF40-008 21074777-21076456 retained_intron
  ENST00000555232 ARHGEF40-005 21070368-21086906 retained_intron
  ENST00000556399 ARHGEF40-002 21070291-21089555 nonsense_mediated_decay
  ENST00000557498 ARHGEF40-009 21087753-21089414 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000298694ENST00000553709ENST00000554514ENST00000555038ENST00000555232ENST00000556399
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000298694 3.457±0.00 2.125±0.00 1.008±0.00 0.603±0.00 4.534±3.67 2.461±0.00 0.522±0.00 3.269±0.00 2.337±0.00 1.640±0.40 1.060±0.00 7.045±0.00 2.973±0.59 N/A
ENST00000553709 9.588±0.00 2.322±0.00 N/A N/A 3.986±3.36 3.737±0.00 1.660±1.40 2.238±1.46 1.153±0.45 4.874±0.00 3.094±0.00 9.384±6.74 6.037±1.57 5.533±3.77
ENST00000554514 N/A N/A N/A 0.907±0.00 13.636±0.00 N/A N/A N/A 3.386±0.00 6.204±0.00 N/A 6.729±4.84 N/A 3.593±0.00
ENST00000555038 N/A N/A N/A N/A N/A 3.920±0.00 1.160±0.00 1.675±0.00 1.919±0.00 N/A N/A N/A N/A N/A
ENST00000555232 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.546±0.00 N/A N/A
ENST00000556399 N/A N/A N/A 1.261±0.00 N/A N/A N/A N/A N/A N/A N/A 0.874±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004TH CIL_0004TH_0001 CGP 14:20999255-21070872
CIL_00027R CIL_00027R_0001 CGP 14:21016763-21070872
CIL_0004Z0 CIL_0004Z0_0002 CGP 14:21070270-21104722

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005737 IEA cytoplasm
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0035023 IEA regulation of Rho protein signal transduction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000078979 ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40 protein_coding Danio_rerio
ENSMUSG00000004562 Arhgef40 Rho guanine nucleotide exchange factor (GEF) 40 protein_coding Mus_musculus

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