C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: alkB, alkylation repair homolog 3 (E. coli)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000166199 ALKBH3 9606 + 11:43880811-43920266 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000302708 ALKBH3-001 43880839-43920212 protein_coding
  ENST00000524742 ALKBH3-007 43880855-43883185 protein_coding
  ENST00000527029 ALKBH3-008 43880831-43882802 retained_intron
  ENST00000529366 ALKBH3-010 43882577-43919042 protein_coding
  ENST00000529434 ALKBH3-004 43918804-43920266 retained_intron
  ENST00000530754 ALKBH3-005 43883082-43901714 retained_intron
  ENST00000530803 ALKBH3-002 43880874-43920266 nonsense_mediated_decay
  ENST00000532129 ALKBH3-012 43889762-43920266 protein_coding
  ENST00000532410 ALKBH3-011 43883083-43920173 processed_transcript
  ENST00000532962 ALKBH3-003 43880811-43920010 nonsense_mediated_decay
  ENST00000533200 ALKBH3-009 43882581-43897700 processed_transcript
  ENST00000534171 ALKBH3-006 43880850-43901544 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000302708ENST00000524742ENST00000527029ENST00000529366ENST00000530754ENST00000532129ENST00000532410ENST00000533200ENST00000534171
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000302708 2.998±0.00 6.902±0.00 N/A 3.162±0.00 2.996±1.58 1.131±0.01 1.976±0.00 3.097±0.00 2.003±1.24 0.923±0.00 3.673±0.00 5.237±2.49 1.542±0.27 5.743±0.82
ENST00000524742 N/A N/A 1.523±0.00 N/A N/A N/A 0.825±0.00 N/A 1.085±0.00 N/A N/A N/A N/A N/A
ENST00000527029 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 6.677±0.00 N/A N/A N/A
ENST00000529366 1.891±0.00 N/A N/A 2.338±0.00 2.227±0.00 N/A N/A N/A N/A N/A 2.982±0.00 N/A N/A N/A
ENST00000530754 3.968±0.00 N/A 1.412±0.00 5.416±0.00 N/A N/A 0.954±0.00 2.227±0.00 N/A N/A 2.797±0.07 3.525±1.49 2.083±0.29 8.384±2.47
ENST00000532129 3.349±0.00 13.831±0.00 N/A 2.916±0.00 3.635±0.00 1.371±0.00 1.809±0.00 5.476±0.00 4.572±0.00 3.613±0.00 4.456±0.12 10.365±0.70 2.211±0.03 5.885±0.00
ENST00000532410 N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.450±0.00 N/A 3.643±0.00 2.543±0.00 6.017±0.00
ENST00000533200 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.322±0.00 1.887±0.00 N/A
ENST00000534171 N/A N/A N/A N/A N/A N/A 0.473±0.00 N/A N/A 1.643±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002UX CIL_0002UX_0002 CGP 11:43556436-43920266
CIL_0002UW CIL_0002UW_0002 CGP 11:43880811-43944338

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005654 TAS nucleoplasm
GO:0005737 IEA cytoplasm
GO:0006281 IDA DNA repair
GO:0006307 IDA DNA dealkylation involved in DNA repair
GO:0008198 IDA ferrous iron binding
GO:0008283 IMP cell proliferation
GO:0016491 IEA oxidoreductase activity
GO:0016706 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0031418 IEA L-ascorbic acid binding
GO:0035552 IDA oxidative single-stranded DNA demethylation
GO:0043734 IDA DNA-N1-methyladenine dioxygenase activity
GO:0051747 IEA cytosine C-5 DNA demethylase activity
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000045606 alkbh3 alkB, alkylation repair homolog 3 (E. coli) protein_coding Danio_rerio
ENSMUSG00000040174 Alkbh3 alkB, alkylation repair homolog 3 (E. coli) protein_coding Mus_musculus

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