C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: alkB, alkylation repair homolog 3 (E. coli)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000302708 ALKBH3-001 ENSG00000166199 9606 + 11:43880839-43920212 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000302708
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000302708 2.998±0.00 6.902±0.00 3.162±0.00 2.996±1.58 1.131±0.01 1.976±0.00 3.097±0.00 2.003±1.24 0.923±0.00 3.673±0.00 5.237±2.49 1.542±0.27 5.743±0.82

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002UX CIL_0002UX_0002 CGP 11:43556436-43920266
CIL_0002UW CIL_0002UW_0002 CGP 11:43880811-43944338

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005654 TAS nucleoplasm
GO:0005737 IEA cytoplasm
GO:0006281 IDA DNA repair
GO:0006307 IDA DNA dealkylation involved in DNA repair
GO:0008198 IDA ferrous iron binding
GO:0008283 IMP cell proliferation
GO:0016491 IEA oxidoreductase activity
GO:0016706 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0031418 IEA L-ascorbic acid binding
GO:0035552 IDA oxidative single-stranded DNA demethylation
GO:0043734 IDA DNA-N1-methyladenine dioxygenase activity
GO:0051747 IEA cytosine C-5 DNA demethylase activity
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000040005 Alkbh3-201 protein_coding Mus_musculus 0 915
ENSMUST00000111240 Alkbh3-001 protein_coding Mus_musculus 0 883
ENSMUST00000126378 Alkbh3-002 protein_coding Mus_musculus 0 586
ENSMUST00000138046 Alkbh3-006 processed_transcript Mus_musculus 0 339
ENSMUST00000127231 Alkbh3-007 processed_transcript Mus_musculus 2.8026e-45 187

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