C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: transmembrane channel-like 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000167895 TMC8 9606 + 17:78130770-78142968 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000318430 TMC8-002 78130786-78142968 protein_coding
  ENST00000589691 TMC8-003 78130788-78142967 protein_coding
  ENST00000590184 TMC8-013 78134949-78138071 processed_transcript
  ENST00000590426 TMC8-012 78130770-78131595 protein_coding
  ENST00000590799 TMC8-006 78130778-78132465 protein_coding
  ENST00000591003 TMC8-009 78137654-78138167 processed_transcript
  ENST00000591144 TMC8-014 78138363-78141229 processed_transcript
  ENST00000591983 TMC8-008 78134868-78138071 retained_intron
  ENST00000592399 TMC8-007 78134868-78137047 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBreastLungOvaryPlacentaENST00000318430ENST00000589691
Transcript ID Adrenal Breast Lung Ovary Placenta
ENST00000318430 40.259±0.00 1.773±0.00 4.811±1.58 N/A 3.758±0.74
ENST00000589691 N/A N/A 5.733±0.00 5.194±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007YS CIL_0007YS_0001 VISTA 17:77940736-78544976
CIL_00009V CIL_00009V_0001 CGP 17:78004168-78132407
CIL_0000A9 CIL_0000A9_0001 CGP 17:78110458-78142968
CIL_00037M CIL_00037M_0001 CGP 17:78130770-78166177

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001558 IDA regulation of cell growth
GO:0005102 IPI receptor binding
GO:0005515 IPI protein binding
GO:0005615 IDA extracellular space
GO:0005737 IDA cytoplasm
GO:0005783 IDA endoplasmic reticulum
GO:0005794 IDA Golgi apparatus
GO:0006811 IEA ion transport
GO:0016021 IEA integral component of membrane
GO:0031965 IDA nuclear membrane
GO:0032091 IDA negative regulation of protein binding
GO:0032460 IDA negative regulation of protein oligomerization
GO:0055069 IDA zinc ion homeostasis
GO:0070062 IDA extracellular vesicular exosome
GO:1902041 IDA regulation of extrinsic apoptotic signaling pathway via death domain receptors

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000060545 TMC8 transmembrane channel-like 8 protein_coding Danio_rerio
ENSMUSG00000050106 Tmc8 transmembrane channel-like gene family 8 protein_coding Mus_musculus

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