C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: transmembrane channel-like gene family 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000050106 Tmc8 10090 + 11:117782076-117793110 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000050874 Tmc8-001 117782297-117793028 protein_coding
  ENSMUST00000106334 Tmc8-004 117782315-117793110 protein_coding
  ENSMUST00000117781 Tmc8-005 117782385-117792883 protein_coding
  ENSMUST00000119455 Tmc8-006 117782658-117793083 protein_coding
  ENSMUST00000127080 Tmc8-002 117782076-117784150 protein_coding
  ENSMUST00000156458 Tmc8-003 117791188-117792613 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartLiverMuscleOvaryPlacentaTestisENSMUST00000050874ENSMUST00000106334ENSMUST00000117781ENSMUST00000119455
Transcript ID Adipose Adrenal Brain Breast Colon Heart Liver Muscle Ovary Placenta Testis
ENSMUST00000050874 4.057±0.00 2.378±0.00 0.467±0.06 6.541±0.26 N/A 0.874±0.13 10.891±5.55 N/A N/A N/A 0.634±0.00
ENSMUST00000106334 1.913±0.00 N/A N/A 11.050±2.21 8.170±0.86 1.188±0.41 9.018±4.05 0.521±0.16 N/A 2.041±0.20 0.623±0.00
ENSMUST00000117781 N/A N/A N/A 2.207±0.00 N/A 2.338±0.00 0.950±0.14 N/A N/A N/A N/A
ENSMUST00000119455 N/A N/A N/A N/A 9.121±0.00 N/A N/A 0.268±0.00 3.192±0.00 3.671±0.32 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007YS CIL_0007YS_0002 VISTA 11:117565410-118167678
CIL_00009V CIL_00009V_0002 CGP 11:117654289-117782198
CIL_0000A9 CIL_0000A9_0002 CGP 11:117765988-117793110
CIL_00037M CIL_00037M_0002 CGP 11:117782076-117807301

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001558 IEA regulation of cell growth
GO:0005102 IEA receptor binding
GO:0005515 IEA protein binding
GO:0005615 IEA extracellular space
GO:0005737 IEA cytoplasm
GO:0005783 IEA endoplasmic reticulum
GO:0005794 IEA Golgi apparatus
GO:0006811 IEA ion transport
GO:0016021 IEA integral component of membrane
GO:0031965 IEA nuclear membrane
GO:0032091 IEA negative regulation of protein binding
GO:0032460 IEA negative regulation of protein oligomerization
GO:0055069 IEA zinc ion homeostasis
GO:0070062 IEA extracellular vesicular exosome
GO:1902041 IEA regulation of extrinsic apoptotic signaling pathway via death domain receptors

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000060545 TMC8 transmembrane channel-like 8 protein_coding Danio_rerio
ENSG00000167895 TMC8 transmembrane channel-like 8 protein_coding Homo_sapiens

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