C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: BCL2/adenovirus E1B 19kDa interacting protein 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000368636 BNIP3-001 ENSG00000176171 9606 - 10:131966455-131981931 protein_coding

Homo sapiens EnsemblGRCh38

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Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000368636
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000368636 7.373±0.00 2.244±0.00 1.854±0.00 22.699±6.27 7.694±5.54 6.596±5.33 15.668±12.57 12.851±0.38 11.472±9.27 2.290±0.19 22.141±17.16 4.369±3.50 8.446±1.67 7.395±3.91

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000478 CIL_000478_0002 CGP 10:131900644-131981931
CIL_0001LG CIL_0001LG_0001 CGP 10:131966455-132184809

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001666 ISS response to hypoxia
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0005635 IDA nuclear envelope
GO:0005654 ISS nucleoplasm
GO:0005737 ISS cytoplasm
GO:0005739 IDA mitochondrion
GO:0005740 IEA mitochondrial envelope
GO:0005741 IDA mitochondrial outer membrane
GO:0005783 IBA endoplasmic reticulum
GO:0006915 IPI apoptotic process
GO:0008219 ISS cell death
GO:0008626 IDA granzyme-mediated apoptotic signaling pathway
GO:0010508 TAS positive regulation of autophagy
GO:0010637 IDA negative regulation of mitochondrial fusion
GO:0016021 IEA integral component of membrane
GO:0016032 IEA viral process
GO:0030425 ISS dendrite
GO:0031307 IDA integral component of mitochondrial outer membrane
GO:0031966 IDA mitochondrial membrane
GO:0035694 IMP mitochondrial protein catabolic process
GO:0042802 IPI identical protein binding
GO:0042803 IDA protein homodimerization activity
GO:0043065 IEA:IDA positive regulation of apoptotic process
GO:0043066 TAS negative regulation of apoptotic process
GO:0043068 IDA positive regulation of programmed cell death
GO:0043243 IDA positive regulation of protein complex disassembly
GO:0043653 IDA mitochondrial fragmentation involved in apoptotic process
GO:0045837 IDA negative regulation of membrane potential
GO:0046902 IDA regulation of mitochondrial membrane permeability
GO:0046982 IDA protein heterodimerization activity
GO:0048102 IEA autophagic cell death
GO:0050873 IEA brown fat cell differentiation
GO:0051020 IPI GTPase binding
GO:0051402 ISS neuron apoptotic process
GO:0051607 IDA defense response to virus
GO:0055093 IEA response to hyperoxia
GO:0070301 IEA cellular response to hydrogen peroxide
GO:0071260 IEP cellular response to mechanical stimulus
GO:0071279 IMP cellular response to cobalt ion
GO:0071456 IMP cellular response to hypoxia
GO:0072593 IDA reactive oxygen species metabolic process
GO:0090141 IDA positive regulation of mitochondrial fission
GO:0090200 IDA positive regulation of release of cytochrome c from mitochondria
GO:0097193 IEA intrinsic apoptotic signaling pathway
GO:0097345 IDA mitochondrial outer membrane permeabilization
GO:1901998 IEA toxin transport
GO:1990144 IMP intrinsic apoptotic signaling pathway in response to hypoxia

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000106112 Bnip3-001 protein_coding Mus_musculus 0 785
ENSMUST00000100687 Gm16439-001 processed_pseudogene Mus_musculus 0 684
ENSMUST00000130500 Bnip3-004 processed_transcript Mus_musculus 0 634
ENSMUST00000141223 Bnip3-005 processed_transcript Mus_musculus 0 239
ENSMUST00000148970 Bnip3-003 processed_transcript Mus_musculus 0 219
ENSMUST00000118706 Gm15936-001 processed_pseudogene Mus_musculus 1.4013e-45 189
ENSMUST00000125359 Bnip3-002 processed_transcript Mus_musculus 6e-34 150

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