C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: major histocompatibility complex, class II, DQ beta 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000179344 HLA-DQB1 9606 - 6:32659467-32668383 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000374943 HLA-DQB1-002 32659467-32666684 protein_coding
  ENST00000399079 HLA-DQB1-004 32659467-32666664 protein_coding
  ENST00000399082 HLA-DQB1-007 32659467-32666652 protein_coding
  ENST00000399084 HLA-DQB1-003 32659467-32668383 protein_coding
  ENST00000434651 HLA-DQB1-001 32659467-32666694 protein_coding
  ENST00000443574 HLA-DQB1-010 32659886-32662450 processed_transcript
  ENST00000460185 HLA-DQB1-009 32659886-32660440 processed_transcript
  ENST00000484729 HLA-DQB1-008 32660107-32666638 nonsense_mediated_decay
  ENST00000487676 HLA-DQB1-005 32659467-32666638 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000374943ENST00000399079ENST00000434651ENST00000460185ENST00000484729ENST00000487676
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000374943 N/A N/A 0.087±0.00 4.814±0.00 N/A N/A 1.177±0.00 N/A 5.928±0.00 N/A N/A 2.947±0.00 N/A
ENST00000399079 N/A N/A 1.097±0.00 1.614±0.00 0.795±0.00 3.635±0.00 N/A 0.842±0.49 29.908±0.00 N/A 1.241±0.00 3.569±0.00 N/A
ENST00000434651 1.686±0.00 29.126±0.00 2.466±0.00 N/A 0.333±0.00 0.451±0.00 11.297±0.00 0.350±0.00 N/A 4.653±0.00 9.568±7.93 2.255±0.65 4.975±0.00
ENST00000460185 N/A N/A 0.814±0.00 19.460±0.00 1.688±0.07 N/A 4.873±0.00 N/A 12.306±0.00 N/A 5.475±2.90 14.240±3.14 N/A
ENST00000484729 17.510±0.00 115.250±0.00 3.945±3.83 16.123±8.17 2.262±2.05 13.068±0.00 9.450±8.33 4.383±0.00 80.160±77.28 5.021±0.01 7.103±5.99 4.673±0.00 9.226±9.00
ENST00000487676 N/A N/A N/A N/A N/A 0.031±0.00 N/A 0.340±0.00 0.490±0.00 N/A 0.153±0.00 N/A 0.048±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001PL CIL_0001PL_0006 CGP 6:32628179-32668383
CIL_0002XS CIL_0002XS_0007 CGP 6:32659467-32747215

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002474 IEA antigen processing and presentation of peptide antigen via MHC class I
GO:0002504 IEA antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
GO:0005515 IEA protein binding
GO:0006955 IEA immune response
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0019882 IEA antigen processing and presentation
GO:0042612 IEA MHC class I protein complex
GO:0042613 IEA MHC class II protein complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000041705 si:busm1-228j01.6 si:busm1-228j01.6 protein_coding Danio_rerio
ENSDARG00000053738 si:dkey-33b17.3 si:dkey-33b17.3 protein_coding Danio_rerio
ENSDARG00000054921 wu:fd58b11 wu:fd58b11 protein_coding Danio_rerio
ENSDARG00000055447 si:busm1-194e12.12 si:busm1-194e12.12 protein_coding Danio_rerio
ENSDARG00000056330 mhc2dbb major histocompatibility complex class II DBB gene protein_coding Danio_rerio
ENSDARG00000074510 si:busm1-104n07.3 si:busm1-104n07.3 protein_coding Danio_rerio
ENSDARG00000076307 si:zfos-2070c2.3 si:zfos-2070c2.3 protein_coding Danio_rerio
ENSDARG00000079105 mhc2dab major histocompatibility complex class II DAB gene protein_coding Danio_rerio
ENSDARG00000088872 si:busm1-228j01.4 si:busm1-228j01.4 protein_coding Danio_rerio
ENSDARG00000093706 si:dkey-33b17.3 si:dkey-33b17.3 protein_coding Danio_rerio
ENSMUSG00000073421 H2-Ab1 histocompatibility 2, class II antigen A, beta 1 protein_coding Mus_musculus

Loading