C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: metastasis associated 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000182979 MTA1 9606 + 14:105419820-105470729 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000331320 MTA1-001 105419822-105470729 protein_coding
  ENST00000405646 MTA1-003 105419938-105470729 protein_coding
  ENST00000406191 MTA1-002 105419892-105470729 protein_coding
  ENST00000424723 MTA1-006 105438715-105460800 nonsense_mediated_decay
  ENST00000426567 MTA1-012 105468109-105470207 protein_coding
  ENST00000434050 MTA1-007 105458344-105470729 protein_coding
  ENST00000435036 MTA1-201 105419820-105470727 protein_coding
  ENST00000438610 MTA1-004 105420016-105470238 nonsense_mediated_decay
  ENST00000469140 MTA1-021 105463553-105467192 retained_intron
  ENST00000481012 MTA1-009 105438672-105463231 retained_intron
  ENST00000481206 MTA1-015 105468975-105470230 retained_intron
  ENST00000481635 MTA1-014 105469467-105470238 retained_intron
  ENST00000490198 MTA1-010 105460881-105465183 retained_intron
  ENST00000494026 MTA1-016 105449043-105458371 retained_intron
  ENST00000494981 MTA1-013 105469069-105470297 protein_coding
  ENST00000498644 MTA1-017 105449240-105460953 protein_coding
  ENST00000550551 MTA1-022 105460894-105464702 protein_coding
  ENST00000550808 MTA1-020 105463259-105464567 retained_intron
  ENST00000551236 MTA1-018 105420019-105454298 nonsense_mediated_decay
  ENST00000552286 MTA1-011 105465334-105470542 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000331320ENST00000405646ENST00000406191ENST00000434050ENST00000435036ENST00000438610ENST00000481012ENST00000481206ENST00000494981ENST00000498644ENST00000550551
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000331320 N/A N/A N/A 0.495±0.00 1.243±0.00 N/A 3.141±2.21 3.968±0.00 2.665±0.00 0.759±0.00 6.728±0.00 7.847±2.59 4.948±0.58 N/A
ENST00000405646 10.342±0.00 N/A N/A N/A N/A 0.732±0.00 N/A N/A N/A 4.528±0.00 N/A 9.992±0.00 2.858±0.00 N/A
ENST00000406191 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.958±0.00 N/A 19.256±3.24
ENST00000434050 N/A 7.529±0.00 N/A 5.333±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000435036 N/A N/A N/A 0.690±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000438610 12.493±0.00 13.450±0.00 0.401±0.00 5.034±4.15 13.241±0.00 18.494±0.00 6.944±0.00 3.779±3.08 3.664±0.00 9.608±0.00 17.764±0.00 9.818±7.25 8.873±0.63 25.353±0.00
ENST00000481012 N/A N/A N/A 1.783±0.00 3.457±0.00 1.648±0.00 N/A N/A N/A 1.806±0.00 N/A 8.485±0.00 7.137±0.00 32.905±0.00
ENST00000481206 N/A N/A N/A N/A N/A N/A N/A 1.345±0.00 N/A N/A N/A N/A N/A N/A
ENST00000494981 N/A N/A N/A N/A N/A N/A 33.795±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000498644 N/A N/A 1.583±0.00 10.637±0.00 N/A 20.822±0.00 N/A 1.783±0.00 5.209±0.00 N/A 6.923±0.00 N/A N/A N/A
ENST00000550551 N/A N/A N/A N/A N/A 5.765±0.00 N/A N/A N/A N/A 5.214±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004Q6 CIL_0004Q6_0001 CGP 14:105300563-105450106
CIL_0006H9 CIL_0006H9_0001 CGP 14:105398579-105470729
CIL_0006HA CIL_0006HA_0001 CGP 14:105419820-105480170

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001046 ISS core promoter sequence-specific DNA binding
GO:0001047 IDA core promoter binding
GO:0001103 IPI RNA polymerase II repressing transcription factor binding
GO:0003677 IEA DNA binding
GO:0003682 IEA chromatin binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0003713 IMP transcription coactivator activity
GO:0003714 IMP transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005635 IDA nuclear envelope
GO:0005737 IDA cytoplasm
GO:0005874 IDA microtubule
GO:0006302 IMP double-strand break repair
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0007165 TAS signal transduction
GO:0008270 IEA zinc ion binding
GO:0010212 IDA response to ionizing radiation
GO:0016581 IEA NuRD complex
GO:0032496 ISS response to lipopolysaccharide
GO:0032922 ISS circadian regulation of gene expression
GO:0040029 IMP regulation of gene expression, epigenetic
GO:0043153 ISS entrainment of circadian clock by photoperiod
GO:0043161 IMP proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0043565 IEA sequence-specific DNA binding
GO:0045475 ISS locomotor rhythm
GO:0050727 ISS regulation of inflammatory response
GO:1902499 IDA positive regulation of protein autoubiquitination

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007198 MTA1 metastasis associated 1 protein_coding Danio_rerio
ENSMUSG00000021144 Mta1 metastasis associated 1 protein_coding Mus_musculus

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