C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glutamate receptor, ionotropic, N-methyl D-aspartate 2A
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000183454 GRIN2A 9606 - 16:9753409-10182754 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000330684 GRIN2A-002 9763061-10182406 protein_coding
  ENST00000396573 GRIN2A-001 9758519-10182754 protein_coding
  ENST00000396575 GRIN2A-201 9753409-9938554 protein_coding
  ENST00000461292 GRIN2A-004 9763175-9763806 processed_transcript
  ENST00000463531 GRIN2A-003 9764839-9769228 processed_transcript
  ENST00000535259 GRIN2A-202 9762676-9938558 protein_coding
  ENST00000562109 GRIN2A-006 9762675-10180432 protein_coding
  ENST00000566665 GRIN2A-005 10179491-10182259 retained_intron
  ENST00000566670 GRIN2A-009 9938154-10031580 processed_transcript
  ENST00000566683 GRIN2A-007 9849887-10031564 processed_transcript
  ENST00000568247 GRIN2A-008 9938067-9970795 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000330684ENST00000396573ENST00000396575ENST00000463531ENST00000535259ENST00000566665ENST00000568247
Transcript ID Adipose Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000330684 N/A N/A 0.107±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 0.188±0.00
ENST00000396573 0.003±0.00 N/A 0.036±0.02 0.212±0.00 0.385±0.22 N/A 0.069±0.06 N/A N/A 0.049±0.00 N/A 0.187±0.00
ENST00000396575 N/A 6.992±1.14 N/A N/A N/A 0.027±0.00 N/A N/A N/A 0.069±0.06 N/A 0.055±0.00
ENST00000463531 N/A N/A N/A N/A N/A N/A N/A N/A 2.293±0.00 N/A N/A N/A
ENST00000535259 0.022±0.00 N/A N/A N/A N/A N/A N/A 0.083±0.00 N/A N/A N/A 1.254±0.00
ENST00000566665 N/A N/A 0.373±0.00 N/A N/A N/A N/A N/A 0.087±0.00 N/A N/A N/A
ENST00000568247 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.100±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000EM CIL_0000EM_0001 CGP 16:9091648-10182754

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001964 IEA startle response
GO:0001975 IEA response to amphetamine
GO:0004970 IEA ionotropic glutamate receptor activity
GO:0004972 IBA N-methyl-D-aspartate selective glutamate receptor activity
GO:0005234 IBA:IEA extracellular-glutamate-gated ion channel activity
GO:0005261 IEA cation channel activity
GO:0005262 IEA calcium channel activity
GO:0005515 IPI protein binding
GO:0005783 IEA endoplasmic reticulum
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006810 TAS transport
GO:0006816 IEA calcium ion transport
GO:0007215 TAS glutamate receptor signaling pathway
GO:0007268 TAS synaptic transmission
GO:0007611 TAS learning or memory
GO:0007612 IEA learning
GO:0007613 IEA memory
GO:0008021 IEA synaptic vesicle
GO:0008104 IEA protein localization
GO:0008270 ISS zinc ion binding
GO:0008542 IEA visual learning
GO:0009611 IEA response to wounding
GO:0009986 ISS cell surface
GO:0014069 IEA postsynaptic density
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0017146 IDA N-methyl-D-aspartate selective glutamate receptor complex
GO:0019233 IEA sensory perception of pain
GO:0022008 IEA neurogenesis
GO:0030054 IEA cell junction
GO:0030425 IBA dendrite
GO:0030431 IEA sleep
GO:0033058 IEA directional locomotion
GO:0034220 IBA ion transmembrane transport
GO:0035235 IBA ionotropic glutamate receptor signaling pathway
GO:0035249 IBA synaptic transmission, glutamatergic
GO:0040011 IEA locomotion
GO:0042177 IEA negative regulation of protein catabolic process
GO:0042391 IEA regulation of membrane potential
GO:0042417 IEA dopamine metabolic process
GO:0042428 IEA serotonin metabolic process
GO:0042493 IEA response to drug
GO:0042734 IEA presynaptic membrane
GO:0043005 IEA neuron projection
GO:0043065 IEA positive regulation of apoptotic process
GO:0045202 IEA synapse
GO:0045211 IBA postsynaptic membrane
GO:0045471 IDA response to ethanol
GO:0048167 IEA regulation of synaptic plasticity
GO:0050804 IEA regulation of synaptic transmission
GO:0051930 IEA regulation of sensory perception of pain
GO:0060078 IEA regulation of postsynaptic membrane potential
GO:0060079 IEA regulation of excitatory postsynaptic membrane potential
GO:0070588 IEA calcium ion transmembrane transport
GO:0097481 IEA neuronal postsynaptic density
GO:0098655 IEA cation transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000034493 grin2aa glutamate receptor, ionotropic, N-methyl D-aspartate 2A, a protein_coding Danio_rerio
ENSDARG00000070543 grin2ab glutamate receptor, ionotropic, N-methyl D-aspartate 2A, b protein_coding Danio_rerio
ENSMUSG00000059003 Grin2a glutamate receptor, ionotropic, NMDA2A (epsilon 1) protein_coding Mus_musculus

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