C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: glutamate receptor, ionotropic, N-methyl D-aspartate 2A
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000396573 GRIN2A-001 ENSG00000183454 9606 - 16:9758519-10182754 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBreastColonHeartLiverOvaryTestisENST00000396573
Transcript ID Adipose Breast Colon Heart Liver Ovary Testis
ENST00000396573 0.003±0.00 0.036±0.02 0.212±0.00 0.385±0.22 0.069±0.06 0.049±0.00 0.187±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000EM CIL_0000EM_0001 CGP 16:9091648-10182754

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001964 IEA startle response
GO:0001975 IEA response to amphetamine
GO:0004970 IEA ionotropic glutamate receptor activity
GO:0004972 IBA N-methyl-D-aspartate selective glutamate receptor activity
GO:0005234 IBA:IEA extracellular-glutamate-gated ion channel activity
GO:0005261 IEA cation channel activity
GO:0005262 IEA calcium channel activity
GO:0005515 IPI protein binding
GO:0005783 IEA endoplasmic reticulum
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006810 TAS transport
GO:0006816 IEA calcium ion transport
GO:0007215 TAS glutamate receptor signaling pathway
GO:0007268 TAS synaptic transmission
GO:0007611 TAS learning or memory
GO:0007612 IEA learning
GO:0007613 IEA memory
GO:0008021 IEA synaptic vesicle
GO:0008104 IEA protein localization
GO:0008270 ISS zinc ion binding
GO:0008542 IEA visual learning
GO:0009611 IEA response to wounding
GO:0009986 ISS cell surface
GO:0014069 IEA postsynaptic density
GO:0016020 IEA membrane
GO:0017146 IDA N-methyl-D-aspartate selective glutamate receptor complex
GO:0019233 IEA sensory perception of pain
GO:0022008 IEA neurogenesis
GO:0030054 IEA cell junction
GO:0030425 IBA dendrite
GO:0030431 IEA sleep
GO:0033058 IEA directional locomotion
GO:0034220 IBA ion transmembrane transport
GO:0035235 IBA ionotropic glutamate receptor signaling pathway
GO:0035249 IBA synaptic transmission, glutamatergic
GO:0040011 IEA locomotion
GO:0042177 IEA negative regulation of protein catabolic process
GO:0042391 IEA regulation of membrane potential
GO:0042417 IEA dopamine metabolic process
GO:0042428 IEA serotonin metabolic process
GO:0042493 IEA response to drug
GO:0042734 IEA presynaptic membrane
GO:0043005 IEA neuron projection
GO:0043065 IEA positive regulation of apoptotic process
GO:0045202 IEA synapse
GO:0045211 IBA postsynaptic membrane
GO:0045471 IDA response to ethanol
GO:0048167 IEA regulation of synaptic plasticity
GO:0050804 IEA regulation of synaptic transmission
GO:0051930 IEA regulation of sensory perception of pain
GO:0060078 IEA regulation of postsynaptic membrane potential
GO:0060079 IEA regulation of excitatory postsynaptic membrane potential
GO:0070588 IEA calcium ion transmembrane transport
GO:0097481 IEA neuronal postsynaptic density
GO:0098655 IEA cation transmembrane transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000115835 Grin2a-001 protein_coding Mus_musculus 0 5962
ENSMUST00000032331 Grin2a-201 protein_coding Mus_musculus 0 5402
ENSMUST00000111905 Grin2b-201 protein_coding Mus_musculus 0 869
ENSMUST00000053880 Grin2b-001 protein_coding Mus_musculus 0 869
ENSMUST00000156482 Grin2a-002 retained_intron Mus_musculus 0 828
ENSMUST00000106554 Grin2c-201 protein_coding Mus_musculus 0 649
ENSMUST00000003351 Grin2c-001 protein_coding Mus_musculus 0 649
ENSMUST00000002848 Grin2d-001 protein_coding Mus_musculus 0 560
ENSDART00000103882 grin2db-201 protein_coding Danio_rerio 0 536
ENSDART00000144062 grin2db-001 protein_coding Danio_rerio 0 536

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