C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000185033 SEMA4B 9606 + 15:90160604-90229679 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000332496 SEMA4B-002 90184963-90229670 protein_coding
  ENST00000411539 SEMA4B-001 90201319-90229676 protein_coding
  ENST00000558051 SEMA4B-014 90201536-90221392 processed_transcript
  ENST00000558065 SEMA4B-004 90219208-90229679 retained_intron
  ENST00000558848 SEMA4B-012 90217617-90220218 retained_intron
  ENST00000558895 SEMA4B-007 90190344-90217554 protein_coding
  ENST00000558975 SEMA4B-015 90221618-90223792 retained_intron
  ENST00000559074 SEMA4B-005 90221750-90229660 protein_coding
  ENST00000559247 SEMA4B-019 90225324-90228407 protein_coding
  ENST00000559300 SEMA4B-011 90184918-90219843 nonsense_mediated_decay
  ENST00000559322 SEMA4B-006 90160604-90217786 protein_coding
  ENST00000559792 SEMA4B-009 90191928-90217810 protein_coding
  ENST00000559983 SEMA4B-017 90225072-90228155 protein_coding
  ENST00000560003 SEMA4B-013 90217056-90217785 retained_intron
  ENST00000560089 SEMA4B-003 90201421-90228747 nonsense_mediated_decay
  ENST00000560263 SEMA4B-008 90191922-90193563 processed_transcript
  ENST00000560993 SEMA4B-016 90223877-90225674 retained_intron
  ENST00000561085 SEMA4B-010 90184920-90221075 protein_coding
  ENST00000561252 SEMA4B-018 90225002-90225608 retained_intron
  ENST00000561321 SEMA4B-020 90227239-90228062 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000332496ENST00000411539ENST00000558051ENST00000558065ENST00000558895ENST00000559074ENST00000560089ENST00000561085ENST00000561321
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000332496 3.682±0.00 8.090±0.00 N/A 5.501±5.34 3.380±2.06 6.728±5.24 4.529±0.00 12.589±11.02 5.579±4.82 23.745±0.00 0.402±0.00 12.012±13.94 14.828±5.02 9.104±0.00
ENST00000411539 0.976±0.00 N/A N/A 0.225±0.00 N/A N/A 1.666±0.00 1.066±0.00 0.736±0.00 N/A N/A 4.049±0.00 5.354±2.93 1.274±0.00
ENST00000558051 N/A N/A 2.381±0.00 1.147±0.00 7.198±0.00 N/A N/A 5.412±0.00 4.298±0.00 N/A N/A 4.800±0.00 N/A N/A
ENST00000558065 N/A N/A 0.332±0.00 N/A N/A 0.360±0.00 N/A N/A N/A 3.414±2.99 N/A N/A N/A 0.913±0.00
ENST00000558895 N/A N/A N/A N/A N/A 7.140±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000559074 N/A N/A N/A N/A N/A 5.790±0.00 N/A N/A 4.541±0.00 N/A 0.541±0.00 5.539±0.00 6.437±0.02 4.508±0.00
ENST00000560089 N/A N/A N/A 0.213±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000561085 N/A N/A N/A 0.965±0.00 N/A N/A N/A N/A 3.315±0.00 2.154±0.00 N/A N/A N/A N/A
ENST00000561321 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.202±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00079J CIL_00079J_0001 CGP 15:90083045-90229679
CIL_0008FE CIL_0008FE_0001 VISTA 15:90100149-90701385
CIL_0000SV CIL_0000SV_0001 CGP 15:90160604-90234047

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004872 IEA receptor activity
GO:0005515 IEA protein binding
GO:0005886 IEA plasma membrane
GO:0007275 IEA multicellular organismal development
GO:0007399 IEA nervous system development
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0030154 IEA cell differentiation
GO:0045202 IEA synapse

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074414 sema4ba sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4Ba protein_coding Danio_rerio
ENSDARG00000076104 SEMA4B (2 of 2) sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B protein_coding Danio_rerio
ENSMUSG00000030539 Sema4b sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B protein_coding Mus_musculus

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