C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: peptidylprolyl isomerase A (cyclophilin A)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000196262 PPIA 9606 + 7:44796680-44824564 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000355968 PPIA-002 44796681-44801631 protein_coding
  ENST00000415933 PPIA-007 44796682-44801624 nonsense_mediated_decay
  ENST00000451562 PPIA-006 44796680-44800011 protein_coding
  ENST00000468812 PPIA-001 44796680-44803117 protein_coding
  ENST00000479021 PPIA-009 44796681-44824564 nonsense_mediated_decay
  ENST00000480603 PPIA-008 44798814-44801624 processed_transcript
  ENST00000481437 PPIA-005 44796680-44799816 retained_intron
  ENST00000489459 PPIA-003 44796681-44801630 protein_coding
  ENST00000494484 PPIA-004 44797973-44801647 retained_intron
  ENST00000620047 PPIA-201 44796681-44801631 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000355968ENST00000415933ENST00000451562ENST00000468812ENST00000489459
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000355968 124.332±0.00 280.588±0.00 46.026±0.00 324.302±39.40 143.531±33.16 183.257±31.41 58.817±41.29 220.912±89.74 138.137±73.84 218.902±106.90 56.025±36.84 242.492±182.40 409.003±87.99 118.519±51.80
ENST00000415933 N/A N/A N/A N/A N/A N/A 26.995±0.00 N/A 65.354±0.00 104.430±0.00 19.535±0.00 213.600±107.87 256.983±146.67 N/A
ENST00000451562 N/A N/A 17.702±0.00 N/A 39.884±0.00 N/A 4.605±0.00 N/A N/A N/A N/A 59.906±0.00 N/A N/A
ENST00000468812 13.491±0.00 37.660±0.00 N/A 22.484±0.00 15.469±0.00 9.339±0.00 1.528±0.00 20.012±0.00 6.518±0.00 N/A 8.194±0.00 17.179±0.00 N/A 10.632±0.00
ENST00000489459 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 11.887±0.00 155.442±130.91 N/A 60.349±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000SC CIL_0000SC_0001 CGP 7:44748581-44824564
CIL_0000SB CIL_0000SB_0001 CGP 7:44796680-44848083

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000413 IDA:IEA protein peptidyl-prolyl isomerization
GO:0002576 TAS platelet degranulation
GO:0003755 IDA:IEA peptidyl-prolyl cis-trans isomerase activity
GO:0005515 IPI protein binding
GO:0005576 TAS extracellular region
GO:0005615 IDA extracellular space
GO:0005634 IDA nucleus
GO:0005829 IDA cytosol
GO:0005925 IDA focal adhesion
GO:0006278 TAS RNA-dependent DNA replication
GO:0006457 TAS:IEA protein folding
GO:0007596 TAS blood coagulation
GO:0016020 IDA membrane
GO:0016032 TAS viral process
GO:0019058 TAS viral life cycle
GO:0019061 TAS uncoating of virus
GO:0019068 TAS virion assembly
GO:0019076 TAS viral release from host cell
GO:0030168 TAS platelet activation
GO:0030260 TAS entry into host cell
GO:0034389 IMP lipid particle organization
GO:0042277 IEA peptide binding
GO:0044822 IDA poly(A) RNA binding
GO:0045069 IMP regulation of viral genome replication
GO:0045070 IMP positive regulation of viral genome replication
GO:0046790 NAS virion binding
GO:0050714 IMP positive regulation of protein secretion
GO:0050900 TAS leukocyte migration
GO:0051082 TAS unfolded protein binding
GO:0070062 IDA extracellular vesicular exosome
GO:0075713 TAS establishment of integrated proviral latency

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000055795 Gm5160 predicted gene 5160 protein_coding Mus_musculus
ENSMUSG00000071866 Ppia peptidylprolyl isomerase A protein_coding Mus_musculus

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