C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: transcription factor 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000196628 TCF4 9606 - 18:55222331-55664787 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000354452 TCF4-201 55222331-55588629 protein_coding
  ENST00000356073 TCF4-002 55222334-55588629 protein_coding
  ENST00000398339 TCF4-004 55227936-55635954 protein_coding
  ENST00000457482 TCF4-015 55227689-55322294 protein_coding
  ENST00000537578 TCF4-003 55227752-55589814 protein_coding
  ENST00000537856 TCF4-013 55227849-55401690 protein_coding
  ENST00000540999 TCF4-007 55227690-55586105 protein_coding
  ENST00000543082 TCF4-009 55227689-55510769 protein_coding
  ENST00000544241 TCF4-011 55227855-55403995 protein_coding
  ENST00000561831 TCF4-016 55227878-55302626 protein_coding
  ENST00000561992 TCF4-010 55227864-55422492 protein_coding
  ENST00000562030 TCF4-014 55350359-55401335 protein_coding
  ENST00000562543 TCF4-040 55350955-55591170 protein_coding
  ENST00000562607 TCF4-035 55275648-55351997 protein_coding
  ENST00000562638 TCF4-043 55275662-55401712 protein_coding
  ENST00000562680 TCF4-018 55227849-55401668 retained_intron
  ENST00000562847 TCF4-029 55350967-55585966 protein_coding
  ENST00000563686 TCF4-017 55264596-55464144 retained_intron
  ENST00000563760 TCF4-037 55254504-55321805 processed_transcript
  ENST00000563824 TCF4-028 55350364-55585437 protein_coding
  ENST00000563888 TCF4-025 55350402-55586119 protein_coding
  ENST00000564228 TCF4-042 55227911-55403714 protein_coding
  ENST00000564343 TCF4-023 55350896-55591279 protein_coding
  ENST00000564403 TCF4-019 55227936-55589803 protein_coding
  ENST00000564999 TCF4-006 55227820-55588610 protein_coding
  ENST00000565018 TCF4-001 55227884-55589520 protein_coding
  ENST00000565124 TCF4-020 55585280-55635948 protein_coding
  ENST00000565393 TCF4-039 55585317-55631362 protein_coding
  ENST00000565580 TCF4-030 55403454-55546934 processed_transcript
  ENST00000565908 TCF4-024 55275707-55588160 protein_coding
  ENST00000566279 TCF4-045 55227911-55588617 protein_coding
  ENST00000566286 TCF4-041 55227911-55588535 protein_coding
  ENST00000566376 TCF4-036 55332067-55403506 processed_transcript
  ENST00000566514 TCF4-027 55269884-55585769 protein_coding
  ENST00000566777 TCF4-032 55275680-55422355 protein_coding
  ENST00000567880 TCF4-046 55227911-55587116 protein_coding
  ENST00000568147 TCF4-026 55350376-55585968 protein_coding
  ENST00000568169 TCF4-021 55269924-55664787 protein_coding
  ENST00000568186 TCF4-033 55275660-55403706 protein_coding
  ENST00000568673 TCF4-008 55227674-55585908 protein_coding
  ENST00000568740 TCF4-005 55227846-55589798 protein_coding
  ENST00000569012 TCF4-034 55269875-55401551 protein_coding
  ENST00000569357 TCF4-022 55403454-55635892 protein_coding
  ENST00000570146 TCF4-038 55259621-55275671 protein_coding
  ENST00000570177 TCF4-012 55227984-55402240 protein_coding
  ENST00000570287 TCF4-044 55227911-55321986 protein_coding
  ENST00000590810 TCF4-047 55350357-55401851 protein_coding
  ENST00000616053 TCF4-202 55222331-55588629 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000354452ENST00000537856ENST00000562680ENST00000563686ENST00000570287ENST00000616053
Transcript ID Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000354452 1.835±0.00 0.424±0.00 4.754±0.00 N/A 2.393±0.00 N/A N/A 8.074±0.00 N/A 0.564±0.00 3.739±1.86 N/A N/A
ENST00000537856 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 7.314±0.00 25.078±0.00 33.153±0.00
ENST00000562680 N/A N/A N/A N/A N/A 3.132±0.00 1.025±0.00 N/A 6.480±0.00 N/A 6.657±0.00 N/A N/A
ENST00000563686 N/A 0.745±0.00 N/A 3.612±0.00 2.276±0.00 2.306±0.00 N/A 5.998±0.00 6.536±0.00 1.156±0.00 N/A N/A N/A
ENST00000570287 N/A 2.153±0.00 N/A N/A N/A N/A N/A N/A N/A 2.780±0.00 N/A N/A N/A
ENST00000616053 N/A N/A N/A N/A N/A N/A N/A N/A 3.169±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007YZ CIL_0007YZ_0001 VISTA 18:54732639-55333995
CIL_0008CT CIL_0008CT_0001 VISTA 18:55004656-55608642
CIL_00091Y CIL_00091Y_0001 VISTA 18:55051447-55652813
CIL_0008DW CIL_0008DW_0001 VISTA 18:55122394-55723848

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000978 ISS RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001011 ISS sequence-specific DNA binding RNA polymerase recruiting transcription factor activity
GO:0001077 ISS RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001087 ISS TFIIB-class binding transcription factor activity
GO:0001093 ISS TFIIB-class transcription factor binding
GO:0003677 IDA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0003714 IEA transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005667 ISS transcription factor complex
GO:0006352 ISS DNA-templated transcription, initiation
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006367 ISS transcription initiation from RNA polymerase II promoter
GO:0008022 IPI protein C-terminus binding
GO:0045666 ISS positive regulation of neuron differentiation
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0046982 ISS protein heterodimerization activity
GO:0046983 IEA protein dimerization activity
GO:0065004 ISS protein-DNA complex assembly
GO:0070888 ISS E-box binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000087652 tcf4 transcription factor 4 protein_coding Danio_rerio
ENSMUSG00000053477 Tcf4 transcription factor 4 protein_coding Mus_musculus

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