C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000197818 SLC9A8 9606 + 20:49812713-49892242 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000361573 SLC9A8-001 49812881-49892242 protein_coding
  ENST00000417961 SLC9A8-201 49812713-49892241 protein_coding
  ENST00000489787 SLC9A8-002 49812894-49815444 processed_transcript
  ENST00000490250 SLC9A8-003 49886371-49892242 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000361573ENST00000417961ENST00000490250
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000361573 2.185±0.00 2.757±0.00 0.462±0.00 0.768±0.09 1.600±0.91 0.822±0.00 1.090±0.59 2.186±0.08 2.232±0.01 1.407±0.00 0.539±0.00 1.434±0.85 2.622±0.52 4.412±0.12
ENST00000417961 N/A N/A N/A 0.499±0.00 N/A N/A N/A N/A N/A 0.771±0.00 2.627±0.00 0.566±0.00 0.388±0.00 0.584±0.00
ENST00000490250 N/A 1.989±0.00 N/A N/A 0.972±0.00 0.176±0.00 0.103±0.00 1.425±0.00 1.730±0.00 0.492±0.29 1.732±0.13 0.795±0.21 N/A 0.823±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008I4 CIL_0008I4_0001 VISTA 20:49375075-49977641
CIL_000277 CIL_000277_0001 CGP 20:49632945-49892242
CIL_00087E CIL_00087E_0001 VISTA 20:49719805-50323644
CIL_0001VJ CIL_0001VJ_0001 CGP 20:49812713-49915508

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000139 TAS Golgi membrane
GO:0005794 IEA Golgi apparatus
GO:0006811 TAS ion transport
GO:0006812 IEA cation transport
GO:0006813 IEA potassium ion transport
GO:0006814 IEA sodium ion transport
GO:0006885 IEA regulation of pH
GO:0015299 IEA solute:proton antiporter activity
GO:0015385 IEA sodium:proton antiporter activity
GO:0015386 IEA potassium:proton antiporter activity
GO:0016021 IEA integral component of membrane
GO:0035725 IEA sodium ion transmembrane transport
GO:0051453 IEA regulation of intracellular pH
GO:0055085 TAS:IEA transmembrane transport
GO:0071805 IEA potassium ion transmembrane transport
GO:1902600 IEA hydrogen ion transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020699 slc9a8 solute carrier family 9 (sodium/hydrogen exchanger), member 8 protein_coding Danio_rerio
ENSMUSG00000039463 Slc9a8 solute carrier family 9 (sodium/hydrogen exchanger), member 8 protein_coding Mus_musculus

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