C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: COP9 signalosome subunit 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000198612 COPS8 9606 + 2:237085312-237100466 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000354371 COPS8-001 237085312-237100466 protein_coding
  ENST00000392008 COPS8-002 237085882-237098618 protein_coding
  ENST00000409334 COPS8-008 237085884-237097933 protein_coding
  ENST00000419015 COPS8-005 237085909-237094186 nonsense_mediated_decay
  ENST00000447464 COPS8-007 237094139-237099143 nonsense_mediated_decay
  ENST00000465362 COPS8-006 237096678-237098160 retained_intron
  ENST00000470452 COPS8-003 237085886-237095881 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000354371ENST00000392008ENST00000409334ENST00000470452
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000354371 1.005±0.00 N/A 0.703±0.00 2.972±1.23 N/A 0.851±0.49 0.450±0.00 1.295±0.41 0.725±0.35 1.048±0.18 N/A 1.668±0.00 1.268±0.00 N/A
ENST00000392008 12.223±0.00 11.398±0.00 N/A 18.048±6.03 7.641±5.30 8.996±7.35 13.257±10.84 9.700±8.04 3.959±1.93 7.247±5.62 16.953±12.22 15.281±9.16 23.611±3.87 30.327±1.62
ENST00000409334 N/A N/A N/A N/A 3.350±0.00 N/A 2.821±0.00 N/A 2.052±0.00 3.194±0.00 4.691±0.00 3.390±0.00 N/A 15.408±0.00
ENST00000470452 N/A N/A N/A N/A N/A N/A N/A 1.056±0.00 N/A N/A N/A 6.509±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000XT CIL_0000XT_0001 CGP 2:236567787-237100466
CIL_0008L9 CIL_0008L9_0001 VISTA 2:237013177-237616630
CIL_0000XQ CIL_0000XQ_0001 CGP 2:237085312-237414375

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0007250 IMP activation of NF-kappaB-inducing kinase activity
GO:0008180 IDA COP9 signalosome
GO:0008285 IMP negative regulation of cell proliferation
GO:0010388 IDA cullin deneddylation
GO:0048471 IDA perinuclear region of cytoplasm
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000024846 cops8 COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis) protein_coding Danio_rerio
ENSMUSG00000034432 Cops8 COP9 (constitutive photomorphogenic) homolog, subunit 8 (Arabidopsis thaliana) protein_coding Mus_musculus

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