C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: major histocompatibility complex, class II, DQ beta 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000232629 HLA-DQB2 9606 - 6:32756098-32763534 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000411527 HLA-DQB2-002 32756098-32763490 protein_coding
  ENST00000427449 HLA-DQB2-004 32756388-32763466 protein_coding
  ENST00000435145 HLA-DQB2-001 32756098-32763532 protein_coding
  ENST00000437316 HLA-DQB2-003 32756098-32763534 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000427449ENST00000435145ENST00000437316
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000427449 1.995±0.00 N/A 1.204±0.00 0.310±0.00 1.864±0.00 N/A 0.466±0.42 2.378±0.00 1.865±0.00 4.095±0.00 1.058±0.36 0.506±0.17 N/A
ENST00000435145 N/A N/A N/A 0.148±0.00 N/A N/A 0.080±0.00 N/A 0.015±0.00 N/A 0.013±0.00 N/A 0.037±0.00
ENST00000437316 6.294±0.00 23.462±0.00 N/A 0.522±0.00 2.876±2.54 2.151±1.68 0.464±0.00 5.208±0.00 0.131±0.00 16.654±12.96 0.833±0.39 0.939±0.98 1.106±0.75

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001PL CIL_0001PL_0009 CGP 6:32741342-32763534
CIL_0001PK CIL_0001PK_0003 CGP 6:32756098-32817048

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000139 TAS Golgi membrane
GO:0002504 IEA antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
GO:0005515 IEA protein binding
GO:0005765 TAS lysosomal membrane
GO:0005886 TAS plasma membrane
GO:0006955 NAS:IEA immune response
GO:0012507 TAS ER to Golgi transport vesicle membrane
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0019882 IEA antigen processing and presentation
GO:0019886 TAS antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0030658 TAS transport vesicle membrane
GO:0030666 TAS endocytic vesicle membrane
GO:0030669 TAS clathrin-coated endocytic vesicle membrane
GO:0031295 TAS T cell costimulation
GO:0032395 NAS MHC class II receptor activity
GO:0032588 TAS trans-Golgi network membrane
GO:0042613 NAS:IEA MHC class II protein complex
GO:0050852 TAS T cell receptor signaling pathway
GO:0060333 TAS interferon-gamma-mediated signaling pathway
GO:0071556 TAS integral component of lumenal side of endoplasmic reticulum membrane

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000041705 si:busm1-228j01.6 si:busm1-228j01.6 protein_coding Danio_rerio
ENSDARG00000053738 si:dkey-33b17.3 si:dkey-33b17.3 protein_coding Danio_rerio
ENSDARG00000054921 wu:fd58b11 wu:fd58b11 protein_coding Danio_rerio
ENSDARG00000055447 si:busm1-194e12.12 si:busm1-194e12.12 protein_coding Danio_rerio
ENSDARG00000056330 mhc2dbb major histocompatibility complex class II DBB gene protein_coding Danio_rerio
ENSDARG00000074510 si:busm1-104n07.3 si:busm1-104n07.3 protein_coding Danio_rerio
ENSDARG00000076307 si:zfos-2070c2.3 si:zfos-2070c2.3 protein_coding Danio_rerio
ENSDARG00000079105 mhc2dab major histocompatibility complex class II DAB gene protein_coding Danio_rerio
ENSDARG00000088872 si:busm1-228j01.4 si:busm1-228j01.4 protein_coding Danio_rerio
ENSDARG00000093706 si:dkey-33b17.3 si:dkey-33b17.3 protein_coding Danio_rerio
ENSMUSG00000073421 H2-Ab1 histocompatibility 2, class II antigen A, beta 1 protein_coding Mus_musculus

Loading