C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: chemokine (C-C motif) receptor 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000272980 CCR6 9606 + 6:166999405-167139141 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000400926 CCR6-201 167111807-167139141 protein_coding
  ENST00000609590 CCR6-001 166999405-167139141 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainColonLiverLungOvaryENST00000400926ENST00000609590
Transcript ID Adrenal Brain Colon Liver Lung Ovary
ENST00000400926 1.082±0.00 N/A N/A N/A N/A N/A
ENST00000609590 N/A 0.257±0.00 0.848±0.00 0.281±0.00 0.535±0.00 1.493±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004W6 CIL_0004W6_0001 CGP 6:166929504-167052713
CIL_0002HA CIL_0002HA_0002 CGP 6:166999182-167139141

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002407 TAS dendritic cell chemotaxis
GO:0004872 TAS receptor activity
GO:0004930 IEA G-protein coupled receptor activity
GO:0004950 TAS chemokine receptor activity
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006928 TAS cellular component movement
GO:0006935 TAS chemotaxis
GO:0006955 TAS immune response
GO:0006959 TAS humoral immune response
GO:0006968 TAS cellular defense response
GO:0007165 TAS signal transduction
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007204 TAS positive regulation of cytosolic calcium ion concentration
GO:0016021 IEA integral component of membrane
GO:0016493 IEA C-C chemokine receptor activity
GO:0045087 TAS innate immune response
GO:0070098 IEA chemokine-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000038968 ccr6b chemokine (C-C motif) receptor 6b protein_coding Danio_rerio
ENSDARG00000087474 ccr6a chemokine (C-C motif) receptor 6a protein_coding Danio_rerio
ENSMUSG00000040899 Ccr6 chemokine (C-C motif) receptor 6 protein_coding Mus_musculus

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