C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: integrin alpha 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000001507 Itga3 10090 - 11:95044474-95076801 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000001548 Itga3-001 95044474-95076714 protein_coding
  ENSMUST00000107739 Itga3-002 95044474-95069198 protein_coding
  ENSMUST00000120375 Itga3-004 95044474-95076801 protein_coding
  ENSMUST00000140342 Itga3-005 95058265-95062271 retained_intron
  ENSMUST00000141693 Itga3-006 95053225-95056195 retained_intron
  ENSMUST00000145671 Itga3-003 95063161-95076797 protein_coding

Mus musculus EnsemblGRCm38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000001548ENSMUST00000107739ENSMUST00000120375ENSMUST00000145671
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000001548 6.695±4.51 18.915±4.09 15.837±2.94 4.637±0.44 7.241±3.05 37.989±7.06 2.273±0.69 12.495±3.35 1.367±0.58 73.423±16.80 0.516±0.22 12.428±5.95 29.192±7.88 0.440±0.19
ENSMUST00000107739 N/A N/A N/A N/A 0.470±0.00 6.551±0.00 N/A N/A N/A N/A 0.203±0.00 N/A N/A N/A
ENSMUST00000120375 N/A N/A N/A 3.655±1.53 N/A N/A 0.739±0.15 N/A N/A N/A 0.351±0.15 3.109±0.00 N/A N/A
ENSMUST00000145671 N/A N/A N/A 16.643±0.00 N/A N/A N/A N/A N/A N/A N/A 23.563±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00088W CIL_00088W_0002 VISTA 11:94580928-95183811
CIL_0007QJ CIL_0007QJ_0002 VISTA 11:95039208-95641127

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001764 IMP neuron migration
GO:0001948 IEA glycoprotein binding
GO:0001968 IEA fibronectin binding
GO:0002020 IEA protease binding
GO:0005178 IEA integrin binding
GO:0005515 IPI protein binding
GO:0005518 IEA collagen binding
GO:0005886 IDA plasma membrane
GO:0005925 IEA focal adhesion
GO:0007155 IEA cell adhesion
GO:0007229 IEA integrin-mediated signaling pathway
GO:0007507 IEA heart development
GO:0007613 IMP memory
GO:0009897 IDA external side of plasma membrane
GO:0009986 IEA cell surface
GO:0010628 IEA positive regulation of gene expression
GO:0010634 IEA positive regulation of epithelial cell migration
GO:0010811 IEA positive regulation of cell-substrate adhesion
GO:0010976 IEA positive regulation of neuron projection development
GO:0016323 IDA basolateral plasma membrane
GO:0017015 IEA regulation of transforming growth factor beta receptor signaling pathway
GO:0019904 IEA protein domain specific binding
GO:0030111 IEA regulation of Wnt signaling pathway
GO:0030324 IEA lung development
GO:0030426 IEA growth cone
GO:0030510 IEA regulation of BMP signaling pathway
GO:0031345 IEA negative regulation of cell projection organization
GO:0031527 ISS filopodium membrane
GO:0034667 IEA integrin alpha3-beta1 complex
GO:0034698 IEA response to gonadotropin
GO:0035024 IGI negative regulation of Rho protein signal transduction
GO:0035640 IGI exploration behavior
GO:0042493 IEA response to drug
GO:0043235 ISO receptor complex
GO:0043236 IEA laminin binding
GO:0043588 IEA skin development
GO:0044708 IMP single-organism behavior
GO:0045202 IDA synapse
GO:0046982 ISS protein heterodimerization activity
GO:0048333 IEA mesodermal cell differentiation
GO:0048471 IEA perinuclear region of cytoplasm
GO:0060076 IDA excitatory synapse
GO:0060135 IEA maternal process involved in female pregnancy
GO:0070062 IEA extracellular vesicular exosome
GO:0071438 ISS invadopodium membrane
GO:0071944 IEA cell periphery
GO:0072006 IEA nephron development
GO:0090004 ISS positive regulation of establishment of protein localization to plasma membrane
GO:0097060 IDA synaptic membrane
GO:0097062 IGI dendritic spine maintenance
GO:0097205 IEA renal filtration

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000012824 itga3b integrin, alpha 3b protein_coding Danio_rerio
ENSDARG00000037917 itga3a integrin, alpha 3a protein_coding Danio_rerio
ENSG00000005884 ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) protein_coding Homo_sapiens

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