C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein kinase, interferon inducible double stranded RNA dependent activator
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000002731 Prkra 10090 - 2:76629898-76648015 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000002808 Prkra-001 76629898-76648015 protein_coding
  ENSMUST00000140493 Prkra-002 76636795-76640733 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000002808ENSMUST00000140493
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000002808 14.827±0.82 27.433±5.54 16.499±1.90 23.843±14.64 8.979±3.28 18.345±6.06 5.199±0.63 9.605±1.26 7.940±1.99 8.517±2.51 1.666±0.28 19.606±6.57 5.511±2.81 7.038±4.19
ENSMUST00000140493 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.899±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000Z1 CIL_0000Z1_0002 CGP 2:76406508-76648015
CIL_0000Z0 CIL_0000Z0_0002 CGP 2:76629898-76658556

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005622 IDA intracellular
GO:0005737 ISS cytoplasm
GO:0006468 IDA protein phosphorylation
GO:0016020 IEA membrane
GO:0030422 ISS production of siRNA involved in RNA interference
GO:0034599 IDA cellular response to oxidative stress
GO:0042473 IMP outer ear morphogenesis
GO:0042474 IMP middle ear morphogenesis
GO:0042803 IEA protein homodimerization activity
GO:0044822 IEA poly(A) RNA binding
GO:0048705 IMP skeletal system morphogenesis
GO:2001244 IDA positive regulation of intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076718 prkra protein kinase, interferon-inducible double stranded RNA dependent activator protein_coding Danio_rerio
ENSG00000180228 PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator protein_coding Homo_sapiens

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