C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cyclin-dependent kinase 12
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000003119 Cdk12 10090 + 11:98203059-98278504 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000003203 Cdk12-002 98203314-98246704 protein_coding
  ENSMUST00000107538 Cdk12-001 98203335-98251044 protein_coding
  ENSMUST00000107539 Cdk12-005 98203059-98251564 protein_coding
  ENSMUST00000125152 Cdk12-007 98263502-98268011 processed_transcript
  ENSMUST00000145113 Cdk12-003 98220401-98225522 processed_transcript
  ENSMUST00000147441 Cdk12-006 98241737-98278504 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000003203ENSMUST00000107538ENSMUST00000107539ENSMUST00000147441
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000003203 N/A N/A N/A 0.551±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 0.829±0.00 N/A
ENSMUST00000107538 1.207±0.56 1.958±0.85 1.758±0.73 1.523±0.46 1.427±0.43 2.274±0.65 N/A 0.829±0.04 1.429±0.46 1.275±0.26 N/A 2.604±1.05 3.083±1.82 1.841±0.35
ENSMUST00000107539 3.461±0.27 1.871±0.67 1.464±0.09 1.758±0.89 3.695±1.11 1.609±0.60 1.957±0.16 3.033±0.26 2.183±0.72 3.349±0.19 0.554±0.07 3.823±1.18 2.283±1.20 3.233±0.30
ENSMUST00000147441 1.989±0.02 1.779±0.58 4.982±0.37 4.206±0.10 2.780±1.16 2.852±0.75 1.130±0.26 2.116±0.36 2.796±1.35 2.817±0.38 0.916±0.39 2.783±1.58 2.531±0.00 3.962±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008SN CIL_0008SN_0002 VISTA 11:97857859-98458466
CIL_00080Z CIL_00080Z_0002 VISTA 11:98039002-98639485
CIL_00098W CIL_00098W_0002 VISTA 11:98077499-98680383
CIL_0007WH CIL_0007WH_0002 VISTA 11:98091902-98695006
CIL_0007D3 CIL_0007D3_0002 CGP 11:98152154-98278504
CIL_0007D4 CIL_0007D4_0002 CGP 11:98203059-98329648

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002944 IEA cyclin K-CDK12 complex
GO:0004672 ISS protein kinase activity
GO:0004693 IEA cyclin-dependent protein serine/threonine kinase activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005730 IEA nucleolus
GO:0006397 IEA mRNA processing
GO:0008353 ISS RNA polymerase II carboxy-terminal domain kinase activity
GO:0008380 ISS RNA splicing
GO:0016607 ISS nuclear speck
GO:0019908 ISS nuclear cyclin-dependent protein kinase holoenzyme complex
GO:0030332 IEA cyclin binding
GO:0043405 ISS regulation of MAP kinase activity
GO:0046777 ISS protein autophosphorylation
GO:0051726 IEA regulation of cell cycle
GO:0070816 ISS phosphorylation of RNA polymerase II C-terminal domain

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000167258 CDK12 cyclin-dependent kinase 12 protein_coding Homo_sapiens

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