C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: calcium channel, voltage-dependent, N type, alpha 1B subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000004113 Cacna1b 10090 - 2:24603887-24763152 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000041342 Cacna1b-002 24606570-24763047 protein_coding
  ENSMUST00000070864 Cacna1b-001 24603887-24763152 protein_coding
  ENSMUST00000100348 Cacna1b-201 24606375-24763047 protein_coding
  ENSMUST00000102939 Cacna1b-004 24603894-24763129 protein_coding
  ENSMUST00000114447 Cacna1b-003 24606570-24763047 protein_coding
  ENSMUST00000124183 Cacna1b-005 24679500-24685868 protein_coding
  ENSMUST00000125798 Cacna1b-008 24609932-24637479 processed_transcript
  ENSMUST00000131861 Cacna1b-006 24606379-24607534 processed_transcript
  ENSMUST00000133892 Cacna1b-009 24607991-24618321 protein_coding
  ENSMUST00000155356 Cacna1b-007 24622599-24632024 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000041342ENSMUST00000070864ENSMUST00000100348ENSMUST00000102939ENSMUST00000114447ENSMUST00000125798ENSMUST00000131861ENSMUST00000133892
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000041342 0.018±0.01 0.203±0.01 N/A N/A 0.160±0.01 0.908±0.41 0.023±0.00 0.007±0.00 N/A N/A 0.009±0.00 0.023±0.01 0.219±0.14 0.228±0.16
ENSMUST00000070864 N/A 0.473±0.24 N/A N/A 0.070±0.00 N/A 0.046±0.00 0.011±0.00 0.013±0.00 N/A 0.006±0.00 0.026±0.02 0.033±0.00 N/A
ENSMUST00000100348 0.014±0.00 0.468±0.00 0.070±0.00 N/A 0.158±0.07 1.192±0.01 N/A N/A 0.004±0.00 0.112±0.00 0.010±0.00 0.019±0.00 N/A 0.287±0.07
ENSMUST00000102939 0.044±0.00 0.197±0.00 0.101±0.03 8.781±4.45 0.119±0.02 0.840±0.35 N/A 0.060±0.01 0.123±0.00 0.173±0.03 0.026±0.00 0.029±0.02 0.128±0.06 0.271±0.00
ENSMUST00000114447 0.017±0.01 N/A N/A 5.168±0.00 0.153±0.01 0.412±0.00 0.022±0.00 0.006±0.00 N/A N/A 0.007±0.00 0.022±0.01 0.264±0.19 0.093±0.00
ENSMUST00000125798 0.056±0.00 N/A N/A N/A 0.332±0.00 N/A N/A 0.312±0.07 N/A N/A 0.054±0.01 N/A N/A N/A
ENSMUST00000131861 N/A 2.108±0.00 N/A N/A 1.379±0.00 N/A N/A 0.034±0.00 N/A 0.631±0.04 0.180±0.02 0.172±0.08 N/A N/A
ENSMUST00000133892 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.162±0.11 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000QH CIL_0000QH_0002 CGP 2:24603887-24919609

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005245 IMP voltage-gated calcium channel activity
GO:0005509 IEA calcium ion binding
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005891 IDA voltage-gated calcium channel complex
GO:0006816 IMP calcium ion transport
GO:0007269 IMP neurotransmitter secretion
GO:0007626 IMP locomotory behavior
GO:0008016 IMP regulation of heart contraction
GO:0008022 IEA protein C-terminus binding
GO:0008217 IMP regulation of blood pressure
GO:0008331 IBA high voltage-gated calcium channel activity
GO:0016020 IDA membrane
GO:0030425 IDA dendrite
GO:0034765 IEA regulation of ion transmembrane transport
GO:0043025 IDA neuronal cell body
GO:0048265 IMP response to pain
GO:0051924 IMP regulation of calcium ion transport
GO:0070509 IBA calcium ion import
GO:0070588 IMP calcium ion transmembrane transport
GO:0086010 IBA membrane depolarization during action potential

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000021735 cacna1ba calcium channel, voltage-dependent, N type, alpha 1B subunit, a protein_coding Danio_rerio
ENSDARG00000079295 cacna1bb calcium channel, voltage-dependent, N type, alpha 1B subunit, b protein_coding Danio_rerio
ENSG00000148408 CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit protein_coding Homo_sapiens

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