C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: tripartite motif-containing 28
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000005566 Trim28 10090 + 7:13024152-13031035 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000005705 Trim28-001 13024152-13031035 protein_coding
  ENSMUST00000123603 Trim28-005 13028405-13029365 retained_intron
  ENSMUST00000123778 Trim28-009 13030372-13031032 retained_intron
  ENSMUST00000125136 Trim28-007 13029091-13029995 retained_intron
  ENSMUST00000128951 Trim28-004 13028021-13029599 retained_intron
  ENSMUST00000129122 Trim28-008 13029704-13030347 retained_intron
  ENSMUST00000142421 Trim28-002 13027617-13029124 retained_intron
  ENSMUST00000148354 Trim28-003 13027829-13028502 retained_intron
  ENSMUST00000149061 Trim28-006 13028880-13029926 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000005705ENSMUST00000123778ENSMUST00000128951
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000005705 58.153±25.79 53.452±6.90 45.327±1.19 96.528±48.16 43.182±8.57 49.572±1.72 18.792±3.92 28.942±3.32 36.659±22.93 41.489±0.85 13.313±1.08 120.245±27.35 58.685±23.57 107.346±31.02
ENSMUST00000123778 N/A N/A N/A N/A 48.270±3.60 N/A 23.384±0.29 36.726±3.13 27.205±0.00 N/A N/A 124.212±0.00 95.800±25.42 N/A
ENSMUST00000128951 N/A N/A N/A 9.349±0.00 N/A N/A N/A N/A N/A N/A N/A 22.423±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00070O CIL_00070O_0002 CGP 7:13004936-13031035
CIL_0006Z2 CIL_0006Z2_0002 CGP 7:13024152-13034777

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IGI negative regulation of transcription from RNA polymerase II promoter
GO:0000785 IDA chromatin
GO:0001701 IMP in utero embryonic development
GO:0001837 IDA epithelial to mesenchymal transition
GO:0003677 IDA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0003713 IDA transcription coactivator activity
GO:0003714 IEA transcription corepressor activity
GO:0004672 IDA protein kinase activity
GO:0004842 IEA ubiquitin-protein transferase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 IDA nucleoplasm
GO:0005719 IDA nuclear euchromatin
GO:0005720 IDA nuclear heterochromatin
GO:0006281 IEA DNA repair
GO:0006351 IEA transcription, DNA-templated
GO:0006468 IDA protein phosphorylation
GO:0007566 IMP embryo implantation
GO:0008270 IEA zinc ion binding
GO:0016567 IEA protein ubiquitination
GO:0016874 IEA ligase activity
GO:0016925 IEA protein sumoylation
GO:0031625 IEA ubiquitin protein ligase binding
GO:0035851 ISS Krueppel-associated box domain binding
GO:0042993 ISS positive regulation of transcription factor import into nucleus
GO:0043045 IMP DNA methylation involved in embryo development
GO:0043565 IDA sequence-specific DNA binding
GO:0044822 IEA poly(A) RNA binding
GO:0045087 IEA innate immune response
GO:0045739 IEA positive regulation of DNA repair
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0046777 IDA protein autophosphorylation
GO:0051259 IEA protein oligomerization
GO:0060028 IMP convergent extension involved in axis elongation
GO:0060669 IMP embryonic placenta morphogenesis
GO:0070087 IEA chromo shadow domain binding
GO:1901536 IMP negative regulation of DNA demethylation
GO:1902187 IEA negative regulation of viral release from host cell
GO:2000653 IMP regulation of genetic imprinting

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000086126 trim33l tripartite motif-containing 33-like protein_coding Danio_rerio
ENSG00000130726 TRIM28 tripartite motif containing 28 protein_coding Homo_sapiens

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