C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: tripartite motif containing 28
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000130726 TRIM28 9606 + 19:58544091-58550722 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000253024 TRIM28-001 58544469-58550716 protein_coding
  ENST00000341753 TRIM28-003 58544473-58550715 protein_coding
  ENST00000593582 TRIM28-004 58544091-58547626 protein_coding
  ENST00000594806 TRIM28-005 58544457-58547888 protein_coding
  ENST00000595028 TRIM28-012 58548869-58549444 retained_intron
  ENST00000595974 TRIM28-013 58549450-58550403 retained_intron
  ENST00000597136 TRIM28-002 58548294-58550722 protein_coding
  ENST00000597172 TRIM28-009 58547559-58548530 retained_intron
  ENST00000597423 TRIM28-007 58547140-58548172 retained_intron
  ENST00000597618 TRIM28-008 58547135-58547906 retained_intron
  ENST00000597968 TRIM28-006 58545167-58545896 protein_coding
  ENST00000597995 TRIM28-010 58547762-58549089 retained_intron
  ENST00000598355 TRIM28-015 58549645-58550649 retained_intron
  ENST00000600840 TRIM28-014 58549556-58550067 retained_intron
  ENST00000601150 TRIM28-011 58547691-58549224 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000253024ENST00000341753ENST00000594806ENST00000597136ENST00000597172ENST00000597618ENST00000597995ENST00000598355
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000253024 20.511±0.00 27.634±0.00 N/A 12.737±11.40 14.850±12.56 29.798±27.58 14.778±13.10 39.926±0.00 10.356±7.14 24.220±22.79 38.512±35.91 76.163±38.91 42.951±33.83 50.574±17.66
ENST00000341753 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 28.668±0.00 N/A N/A
ENST00000594806 N/A N/A 3.291±0.00 3.813±0.00 2.922±0.00 3.737±0.00 N/A 3.863±0.00 5.030±0.00 2.859±0.00 N/A N/A 33.980±0.00 46.344±0.00
ENST00000597136 34.785±0.00 52.078±0.00 N/A 23.245±0.00 40.618±0.00 53.591±0.00 N/A 26.479±0.00 8.226±0.00 32.865±0.00 45.421±0.00 70.492±15.57 37.263±14.87 62.940±23.07
ENST00000597172 N/A N/A N/A N/A 3.352±0.00 3.930±0.00 N/A N/A 3.684±0.00 N/A N/A 2.717±0.00 N/A N/A
ENST00000597618 N/A N/A 1.852±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000597995 N/A N/A N/A N/A N/A 2.525±0.00 N/A 1.691±0.00 N/A 2.485±0.00 N/A 3.151±0.00 N/A N/A
ENST00000598355 N/A 52.704±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00070O CIL_00070O_0001 CGP 19:58513530-58550722
CIL_0006Z2 CIL_0006Z2_0001 CGP 19:58544091-58555124

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000785 IEA chromatin
GO:0001701 IEA in utero embryonic development
GO:0001837 ISS epithelial to mesenchymal transition
GO:0003677 IDA DNA binding
GO:0003700 ISS sequence-specific DNA binding transcription factor activity
GO:0003713 IEA transcription coactivator activity
GO:0003714 IDA transcription corepressor activity
GO:0004672 IEA protein kinase activity
GO:0004842 IDA ubiquitin-protein transferase activity
GO:0005515 IPI:IEA protein binding
GO:0005622 IEA intracellular
GO:0005634 ISS nucleus
GO:0005654 TAS nucleoplasm
GO:0005719 IEA nuclear euchromatin
GO:0005720 IEA nuclear heterochromatin
GO:0006281 IDA DNA repair
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0006468 IEA protein phosphorylation
GO:0007566 IEA embryo implantation
GO:0008270 IEA:IDA zinc ion binding
GO:0010467 TAS gene expression
GO:0016567 IDA protein ubiquitination
GO:0016874 IEA ligase activity
GO:0016925 IEA protein sumoylation
GO:0031625 IDA ubiquitin protein ligase binding
GO:0035851 IDA Krueppel-associated box domain binding
GO:0042993 IDA positive regulation of transcription factor import into nucleus
GO:0043045 IEA DNA methylation involved in embryo development
GO:0043565 ISS sequence-specific DNA binding
GO:0044822 IDA poly(A) RNA binding
GO:0045087 IDA innate immune response
GO:0045739 IDA positive regulation of DNA repair
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0046777 IEA protein autophosphorylation
GO:0051259 IDA protein oligomerization
GO:0060028 IEA convergent extension involved in axis elongation
GO:0060669 IEA embryonic placenta morphogenesis
GO:0070087 IPI chromo shadow domain binding
GO:1901536 IEA negative regulation of DNA demethylation
GO:1902187 IDA negative regulation of viral release from host cell
GO:2000653 IEA regulation of genetic imprinting

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000086126 trim33l tripartite motif-containing 33-like protein_coding Danio_rerio
ENSMUSG00000005566 Trim28 tripartite motif-containing 28 protein_coding Mus_musculus

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