C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: transient receptor potential cation channel, subfamily V, member 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000014158 Trpv4 10090 - 5:114622152-114658421 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000071968 Trpv4-001 114622152-114658421 protein_coding
  ENSMUST00000112217 Trpv4-007 114622653-114644899 protein_coding
  ENSMUST00000112219 Trpv4-006 114622653-114644899 protein_coding
  ENSMUST00000112222 Trpv4-005 114622653-114644899 protein_coding
  ENSMUST00000112225 Trpv4-002 114622154-114658418 protein_coding
  ENSMUST00000133019 Trpv4-004 114622157-114636261 retained_intron
  ENSMUST00000141828 Trpv4-003 114626744-114630638 processed_transcript

Mus musculus EnsemblGRCm38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000071968ENSMUST00000112217ENSMUST00000112219ENSMUST00000112222ENSMUST00000112225ENSMUST00000133019ENSMUST00000141828
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000071968 3.735±0.79 0.894±0.32 14.621±1.55 0.187±0.02 4.240±1.67 0.974±0.27 1.142±0.41 32.430±5.52 0.098±0.06 1.680±0.64 0.225±0.05 2.222±0.31 0.183±0.01 N/A
ENSMUST00000112217 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.438±0.00 0.471±0.00 N/A 0.154±0.00
ENSMUST00000112219 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.395±0.07 N/A
ENSMUST00000112222 N/A N/A N/A 0.361±0.00 1.247±0.00 N/A 0.618±0.00 N/A N/A N/A N/A 0.888±0.21 N/A 0.051±0.00
ENSMUST00000112225 1.741±0.76 0.902±0.28 9.358±1.77 0.142±0.03 1.542±0.44 N/A 0.563±0.00 18.626±2.16 0.057±0.02 1.165±0.36 0.201±0.03 2.818±1.16 0.382±0.20 0.195±0.05
ENSMUST00000133019 0.969±0.10 0.414±0.11 4.253±0.37 0.173±0.01 1.010±0.16 0.377±0.20 N/A N/A 0.103±0.06 0.621±0.14 0.111±0.00 0.811±0.38 0.115±0.03 0.145±0.01
ENSMUST00000141828 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.356±0.00 N/A 0.130±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001JO CIL_0001JO_0003 CGP 5:114568016-114658421
CIL_00062E CIL_00062E_0003 CGP 5:114622152-114690984

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003779 IEA actin binding
GO:0005034 IDA osmosensor activity
GO:0005080 IEA protein kinase C binding
GO:0005261 ISS cation channel activity
GO:0005262 IDA calcium channel activity
GO:0005515 IPI protein binding
GO:0005516 ISS calmodulin binding
GO:0005524 IEA ATP binding
GO:0005881 IEA cytoplasmic microtubule
GO:0005886 ISS plasma membrane
GO:0005912 IDA adherens junction
GO:0005925 IEA focal adhesion
GO:0005929 IDA cilium
GO:0006874 ISS cellular calcium ion homeostasis
GO:0006970 IDA response to osmotic stress
GO:0006971 IEA hypotonic response
GO:0007015 IEA actin filament organization
GO:0007043 IMP cell-cell junction assembly
GO:0007204 IEA positive regulation of cytosolic calcium ion concentration
GO:0007231 IDA osmosensory signaling pathway
GO:0008017 IEA microtubule binding
GO:0009986 IEA cell surface
GO:0010977 IEA negative regulation of neuron projection development
GO:0016021 IEA integral component of membrane
GO:0019901 IPI protein kinase binding
GO:0030027 IEA lamellipodium
GO:0030103 IMP vasopressin secretion
GO:0030175 IEA filopodium
GO:0030426 IEA growth cone
GO:0030864 IEA cortical actin cytoskeleton
GO:0031117 IEA positive regulation of microtubule depolymerization
GO:0031410 IEA cytoplasmic vesicle
GO:0031532 IEA actin cytoskeleton reorganization
GO:0032587 IEA ruffle membrane
GO:0034605 IMP cellular response to heat
GO:0042169 IPI SH2 domain binding
GO:0042538 IMP hyperosmotic salinity response
GO:0043014 IEA alpha-tubulin binding
GO:0043622 IEA cortical microtubule organization
GO:0046785 IEA microtubule polymerization
GO:0047484 IMP regulation of response to osmotic stress
GO:0048487 IEA beta-tubulin binding
GO:0051015 IEA actin filament binding
GO:0070509 IDA calcium ion import
GO:0070588 IEA calcium ion transmembrane transport
GO:0071470 IMP cellular response to osmotic stress
GO:0071476 IDA cellular hypotonic response

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000061941 trpv4 transient receptor potential cation channel, subfamily V, member 4 protein_coding Danio_rerio
ENSG00000111199 TRPV4 transient receptor potential cation channel, subfamily V, member 4 protein_coding Homo_sapiens

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