C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: T-box 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000018263 Tbx5 10090 + 5:119834663-119885218 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000018407 Tbx5-201 119834663-119885218 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000018407
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000018407 0.245±0.20 0.208±0.08 1.759±0.07 0.028±0.00 0.595±0.30 0.022±0.01 5.500±2.16 0.026±0.01 0.016±0.02 7.312±2.92 0.016±0.01 0.024±0.01 0.399±0.30 1.291±0.09

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008K7 CIL_0008K7_0002 VISTA 5:119367993-119968855
CIL_0008K6 CIL_0008K6_0002 VISTA 5:119368986-119969581
CIL_00092A CIL_00092A_0002 VISTA 5:119496787-120097947
CIL_00095S CIL_00095S_0002 VISTA 5:119521983-120124240
CIL_0004YZ CIL_0004YZ_0002 CGP 5:119670669-119885218
CIL_0008CB CIL_0008CB_0002 VISTA 5:119676561-120277190

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000977 IDA RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001228 IDA RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0002009 IMP morphogenesis of an epithelium
GO:0003166 IGI bundle of His development
GO:0003181 IGI atrioventricular valve morphogenesis
GO:0003197 IGI endocardial cushion development
GO:0003218 IMP cardiac left ventricle formation
GO:0003229 IGI ventricular cardiac muscle tissue development
GO:0003281 IMP ventricular septum development
GO:0003283 IMP atrial septum development
GO:0003677 ISS DNA binding
GO:0003700 ISS sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0005667 IPI transcription factor complex
GO:0005737 ISS cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IMP regulation of transcription, DNA-templated
GO:0007267 ISS cell-cell signaling
GO:0007389 IMP pattern specification process
GO:0007507 ISS heart development
GO:0008134 IEA transcription factor binding
GO:0008285 ISS negative regulation of cell proliferation
GO:0030262 IEA apoptotic nuclear changes
GO:0030324 IMP lung development
GO:0030326 ISS embryonic limb morphogenesis
GO:0030336 ISS negative regulation of cell migration
GO:0035115 ISS embryonic forelimb morphogenesis
GO:0035136 IMP forelimb morphogenesis
GO:0043565 ISS sequence-specific DNA binding
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0051891 ISS positive regulation of cardioblast differentiation
GO:0055007 IMP cardiac muscle cell differentiation
GO:0060039 ISS pericardium development
GO:0060044 ISS negative regulation of cardiac muscle cell proliferation
GO:0060045 IGI positive regulation of cardiac muscle cell proliferation
GO:0060413 IGI atrial septum morphogenesis
GO:0072513 IMP positive regulation of secondary heart field cardioblast proliferation
GO:1900117 ISS regulation of execution phase of apoptosis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000024894 tbx5a T-box 5a protein_coding Danio_rerio
ENSG00000089225 TBX5 T-box 5 protein_coding Homo_sapiens

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