C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: serine/arginine-rich splicing factor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000018379 Srsf1 10090 + 11:88047373-88053755 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000079866 Srsf1-003 88047718-88051490 protein_coding
  ENSMUST00000107920 Srsf1-006 88047803-88050410 protein_coding
  ENSMUST00000132983 Srsf1-004 88049412-88051051 retained_intron
  ENSMUST00000134824 Srsf1-002 88048567-88051472 nonsense_mediated_decay
  ENSMUST00000139129 Srsf1-001 88047373-88053755 protein_coding
  ENSMUST00000171976 Srsf1-007 88047725-88048826 retained_intron
  ENSMUST00000172186 Srsf1-005 88048589-88051122 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000079866ENSMUST00000107920ENSMUST00000132983ENSMUST00000134824ENSMUST00000139129ENSMUST00000171976ENSMUST00000172186
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000079866 22.797±6.55 58.028±25.89 44.159±9.07 49.398±36.47 18.417±6.74 15.293±3.87 10.141±1.52 11.240±1.83 37.323±29.49 20.259±1.45 11.090±1.26 27.151±15.49 29.947±14.88 17.700±1.65
ENSMUST00000107920 25.780±0.00 N/A N/A N/A 14.190±1.04 23.324±5.67 9.133±1.69 17.483±0.94 28.416±26.77 15.735±0.66 N/A 35.203±4.89 54.556±21.53 27.293±1.20
ENSMUST00000132983 N/A N/A 88.764±0.00 95.184±56.29 20.353±0.00 N/A 10.272±0.32 N/A N/A N/A N/A 69.810±16.66 68.030±43.44 38.859±15.05
ENSMUST00000134824 N/A N/A N/A 59.649±0.00 N/A N/A N/A N/A N/A N/A N/A 93.502±39.96 86.919±42.31 67.890±0.00
ENSMUST00000139129 6.906±3.39 19.528±0.00 16.543±2.23 26.182±16.94 3.523±0.74 6.998±3.13 3.593±0.67 4.389±1.14 17.786±13.28 5.936±0.10 5.012±1.75 12.456±5.79 10.781±5.77 6.057±0.90
ENSMUST00000171976 36.972±12.30 97.327±47.95 N/A N/A 38.244±11.80 21.210±5.12 N/A 18.387±1.98 7.698±1.16 20.752±0.00 N/A 34.142±9.30 N/A N/A
ENSMUST00000172186 N/A N/A N/A 144.207±0.00 N/A N/A N/A N/A N/A N/A N/A 379.824±0.00 310.035±183.09 228.710±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009DL CIL_0009DL_0002 VISTA 11:87880548-88481652
CIL_0009DM CIL_0009DM_0002 VISTA 11:87974079-88576075
CIL_00039M CIL_00039M_0002 CGP 11:87979525-88053755

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0000395 ISS mRNA 5'-splice site recognition
GO:0001701 IMP in utero embryonic development
GO:0003723 ISS RNA binding
GO:0003729 ISO mRNA binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 ISS nucleoplasm
GO:0005737 IEA cytoplasm
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006417 IEA regulation of translation
GO:0008380 IGI RNA splicing
GO:0016607 IDA nuclear speck
GO:0035145 IEA exon-exon junction complex
GO:0043488 IEA regulation of mRNA stability
GO:0044822 IEA poly(A) RNA binding
GO:0048024 IEA regulation of mRNA splicing, via spliceosome
GO:0050733 IPI RS domain binding
GO:0051028 IEA mRNA transport
GO:0060048 IGI cardiac muscle contraction
GO:0070062 IEA extracellular vesicular exosome
GO:0071013 IEA catalytic step 2 spliceosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000017843 srsf1b serine/arginine-rich splicing factor 1b protein_coding Danio_rerio
ENSG00000136450 SRSF1 serine/arginine-rich splicing factor 1 protein_coding Homo_sapiens

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