C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: TNFAIP3 interacting protein 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020400 Tnip1 10090 - 11:54910785-54962917 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000018482 Tnip1-001 54910787-54962912 protein_coding
  ENSMUST00000102730 Tnip1-007 54910787-54962910 protein_coding
  ENSMUST00000102731 Tnip1-003 54910787-54962917 protein_coding
  ENSMUST00000108885 Tnip1-008 54910789-54962909 protein_coding
  ENSMUST00000108886 Tnip1-002 54910787-54962916 protein_coding
  ENSMUST00000108889 Tnip1-201 54910785-54956122 protein_coding
  ENSMUST00000124304 Tnip1-006 54910787-54956104 processed_transcript
  ENSMUST00000126703 Tnip1-004 54926704-54956122 protein_coding
  ENSMUST00000132224 Tnip1-011 54918611-54921075 retained_intron
  ENSMUST00000132776 Tnip1-010 54940613-54962909 processed_transcript
  ENSMUST00000151736 Tnip1-009 54940559-54956087 processed_transcript
  ENSMUST00000155316 Tnip1-005 54934013-54956047 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000018482ENSMUST00000102730ENSMUST00000108886ENSMUST00000108889ENSMUST00000124304ENSMUST00000126703
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000018482 1.368±0.03 N/A N/A 1.046±0.00 1.410±0.00 N/A 1.706±0.35 1.586±0.00 0.790±0.09 N/A N/A 7.078±2.34 2.714±0.00 0.655±0.20
ENSMUST00000102730 3.996±1.68 N/A 5.165±1.75 2.612±0.00 6.490±0.00 8.846±1.93 2.943±0.97 3.753±0.40 0.976±0.40 4.601±2.40 3.596±0.83 10.066±4.17 7.583±4.60 0.658±0.00
ENSMUST00000108886 3.302±1.83 6.122±2.36 1.928±0.16 1.035±0.22 6.776±2.90 10.399±3.92 3.866±1.08 4.223±0.70 0.748±0.25 3.729±0.48 2.696±0.00 14.301±6.69 7.462±5.72 0.478±0.07
ENSMUST00000108889 2.277±0.10 4.778±0.50 2.395±0.22 2.249±2.27 N/A 8.508±0.55 N/A 1.876±0.54 1.110±0.26 3.579±0.01 3.736±0.70 5.293±0.41 2.820±0.57 0.796±0.25
ENSMUST00000124304 N/A N/A N/A 11.961±0.00 N/A N/A N/A N/A N/A N/A N/A 36.654±0.00 11.231±6.11 4.138±0.00
ENSMUST00000126703 3.883±0.00 9.611±0.66 N/A 1.713±0.00 11.694±3.32 22.710±4.42 N/A N/A 1.595±0.40 7.567±0.53 N/A 11.806±1.06 N/A 1.160±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001KS CIL_0001KS_0002 CGP 11:54902453-54962917
CIL_0001KR CIL_0001KR_0002 CGP 11:54910785-55033445

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002755 IDA MyD88-dependent toll-like receptor signaling pathway
GO:0004843 IEA ubiquitin-specific protease activity
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0006954 IEA inflammatory response
GO:0007159 IEA leukocyte cell-cell adhesion
GO:0008152 ISS metabolic process
GO:0009101 IEA glycoprotein biosynthetic process
GO:0031593 IDA polyubiquitin binding
GO:0043124 IEA negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0050729 IMP positive regulation of inflammatory response
GO:0051019 IEA mitogen-activated protein kinase binding
GO:0070373 IEA negative regulation of ERK1 and ERK2 cascade
GO:0085032 IEA modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015653 tnip1 TNFAIP3 interacting protein 1 protein_coding Danio_rerio
ENSG00000145901 TNIP1 TNFAIP3 interacting protein 1 protein_coding Homo_sapiens

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