C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: TNF receptor-associated factor 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000021277 Traf3 10090 + 12:111166370-111267153 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000021706 Traf3-001 111166463-111267148 protein_coding
  ENSMUST00000060274 Traf3-201 111166548-111267144 protein_coding
  ENSMUST00000117269 Traf3-002 111166370-111267153 protein_coding
  ENSMUST00000139162 Traf3-003 111166486-111239077 protein_coding
  ENSMUST00000143395 Traf3-004 111248483-111262560 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000021706ENSMUST00000060274ENSMUST00000117269ENSMUST00000143395
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000021706 3.858±2.12 4.424±2.88 6.707±1.67 5.639±3.44 3.190±0.95 2.403±0.66 2.184±0.38 1.862±0.43 1.155±0.45 2.077±0.39 2.518±0.54 2.322±0.82 3.281±1.15 N/A
ENSMUST00000060274 N/A N/A N/A 2.766±0.00 N/A N/A N/A N/A 0.417±0.00 N/A 0.430±0.10 0.825±0.01 N/A N/A
ENSMUST00000117269 N/A N/A N/A 0.994±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000143395 N/A N/A N/A 5.593±0.00 N/A N/A N/A N/A N/A N/A N/A 5.086±0.00 5.562±0.30 0.608±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009AG CIL_0009AG_0002 VISTA 12:110842738-111443613
CIL_00040T CIL_00040T_0002 CGP 12:111166370-111276426

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001817 IEA:IMP regulation of cytokine production
GO:0002224 IMP toll-like receptor signaling pathway
GO:0004842 IEA ubiquitin-protein transferase activity
GO:0005164 IEA tumor necrosis factor receptor binding
GO:0005515 IPI protein binding
GO:0005768 IEA endosome
GO:0006915 IEA apoptotic process
GO:0008063 IEA Toll signaling pathway
GO:0008270 IEA zinc ion binding
GO:0009898 IDA cytoplasmic side of plasma membrane
GO:0016567 IEA protein ubiquitination
GO:0016874 IEA ligase activity
GO:0019901 IPI protein kinase binding
GO:0030162 IMP regulation of proteolysis
GO:0031625 IEA ubiquitin protein ligase binding
GO:0031996 IEA thioesterase binding
GO:0032088 IEA:IMP negative regulation of NF-kappaB transcription factor activity
GO:0032648 IMP regulation of interferon-beta production
GO:0033209 IEA:ISS tumor necrosis factor-mediated signaling pathway
GO:0035631 IDA CD40 receptor complex
GO:0042981 IEA regulation of apoptotic process
GO:0045087 IEA innate immune response
GO:0050688 IEA:IMP regulation of defense response to virus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000022000 traf3 TNF receptor-associated factor 3 protein_coding Danio_rerio
ENSG00000131323 TRAF3 TNF receptor-associated factor 3 protein_coding Homo_sapiens

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