C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: adenylosuccinate lyase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000022407 Adsl 10090 + 15:80948490-80970947 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000023043 Adsl-001 80948490-80970947 protein_coding
  ENSMUST00000163575 Adsl-008 80961213-80963844 retained_intron
  ENSMUST00000164371 Adsl-005 80948542-80955888 retained_intron
  ENSMUST00000164806 Adsl-003 80948548-80968748 protein_coding
  ENSMUST00000166711 Adsl-002 80948512-80969119 nonsense_mediated_decay
  ENSMUST00000168756 Adsl-004 80948548-80968748 protein_coding
  ENSMUST00000169238 Adsl-006 80948537-80964036 nonsense_mediated_decay
  ENSMUST00000170354 Adsl-007 80948777-80952288 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000023043ENSMUST00000164371ENSMUST00000164806ENSMUST00000166711ENSMUST00000168756
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000023043 N/A 1.900±0.04 N/A N/A N/A 1.288±0.00 N/A N/A 0.954±0.00 N/A N/A 1.618±0.93 N/A N/A
ENSMUST00000164371 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 33.175±0.00 45.547±0.00 N/A
ENSMUST00000164806 14.284±3.95 5.404±0.90 13.807±3.37 11.318±1.25 10.237±6.53 9.879±4.23 19.812±3.89 10.895±3.38 11.595±8.47 10.336±3.11 28.942±7.92 16.755±4.94 13.739±9.50 8.564±0.68
ENSMUST00000166711 8.642±1.78 8.115±1.59 12.345±1.84 8.385±1.09 8.457±2.27 6.560±1.18 9.885±1.17 7.161±2.17 7.578±5.45 5.902±0.88 19.839±8.13 12.103±3.86 12.869±6.83 6.735±1.85
ENSMUST00000168756 4.644±0.88 5.359±1.76 5.609±0.00 3.653±0.00 5.711±1.12 4.774±0.27 7.820±0.99 9.151±0.62 4.089±1.81 5.817±0.00 10.686±0.00 4.763±0.16 4.158±1.30 2.602±0.25

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006F2 CIL_0006F2_0002 CGP 15:80711319-80970947

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001666 IEA response to hypoxia
GO:0004018 ISA N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity
GO:0005739 IDA mitochondrion
GO:0005829 IEA cytosol
GO:0006163 IEA purine nucleotide metabolic process
GO:0006167 ISA AMP biosynthetic process
GO:0006189 IEA 'de novo' IMP biosynthetic process
GO:0007584 IEA response to nutrient
GO:0008152 IEA metabolic process
GO:0009060 IEA aerobic respiration
GO:0009156 IEA ribonucleoside monophosphate biosynthetic process
GO:0014850 IEA response to muscle activity
GO:0042594 IEA response to starvation
GO:0044208 IEA 'de novo' AMP biosynthetic process
GO:0051262 IEA protein tetramerization
GO:0070626 IEA (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000017049 adsl adenylosuccinate lyase protein_coding Danio_rerio
ENSG00000239900 ADSL adenylosuccinate lyase protein_coding Homo_sapiens

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