C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: transferrin receptor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000022797 Tfrc 10090 + 16:32608920-32632794 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000023486 Tfrc-001 32608920-32632794 protein_coding
  ENSMUST00000120680 Tfrc-002 32608983-32623741 protein_coding
  ENSMUST00000124243 Tfrc-003 32609250-32613226 protein_coding
  ENSMUST00000128285 Tfrc-004 32624442-32632790 retained_intron
  ENSMUST00000137901 Tfrc-005 32615232-32617156 retained_intron
  ENSMUST00000155929 Tfrc-006 32618279-32620881 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000023486ENSMUST00000120680ENSMUST00000128285
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000023486 2.801±0.89 2.382±0.53 3.036±0.37 4.207±1.78 2.910±0.48 6.724±1.88 14.307±3.89 5.264±0.90 46.123±53.36 7.754±0.56 25.111±2.65 3.365±1.68 76.306±54.82 3.030±0.93
ENSMUST00000120680 N/A N/A N/A 8.685±0.00 N/A N/A N/A N/A N/A N/A N/A 4.905±3.26 110.278±5.65 2.103±0.00
ENSMUST00000128285 2.451±0.31 1.088±0.23 3.444±0.85 6.266±1.41 3.071±0.63 5.857±1.99 6.715±1.66 2.721±0.47 30.781±38.02 5.174±0.93 6.134±2.41 2.229±1.17 20.246±3.16 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008QR CIL_0008QR_0002 VISTA 16:32268412-32870796
CIL_0007CJ CIL_0007CJ_0003 CGP 16:32608920-32683493

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003725 ISO double-stranded RNA binding
GO:0004998 TAS transferrin receptor activity
GO:0005381 TAS iron ion transmembrane transporter activity
GO:0005515 IPI protein binding
GO:0005576 IEA extracellular region
GO:0005615 IEA extracellular space
GO:0005768 IDA endosome
GO:0005886 IDA plasma membrane
GO:0005905 IDA coated pit
GO:0006879 IMP cellular iron ion homeostasis
GO:0006898 IEA receptor-mediated endocytosis
GO:0009897 IDA external side of plasma membrane
GO:0009986 ISO cell surface
GO:0016021 IEA integral component of membrane
GO:0016023 ISO cytoplasmic membrane-bounded vesicle
GO:0030316 IMP osteoclast differentiation
GO:0031982 IEA vesicle
GO:0033572 IEA transferrin transport
GO:0034755 TAS iron ion transmembrane transport
GO:0042802 IEA identical protein binding
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0044822 IEA poly(A) RNA binding
GO:0045780 IDA positive regulation of bone resorption
GO:0048471 IDA perinuclear region of cytoplasm
GO:0055037 ISO recycling endosome
GO:0070062 IDA extracellular vesicular exosome
GO:0072562 IEA blood microparticle
GO:0097286 IEA iron ion import

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000012552 tfr1b transferrin receptor 1b protein_coding Danio_rerio
ENSDARG00000058784 tfr1a transferrin receptor 1a protein_coding Danio_rerio
ENSDARG00000077372 tfr1b transferrin receptor 1b protein_coding Danio_rerio
ENSG00000072274 TFRC transferrin receptor protein_coding Homo_sapiens

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