C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: sodium channel, voltage-gated, type VIII, alpha
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000023033 Scn8a 10090 + 15:100870683-101045929 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000082209 Scn8a-201 100870683-101045929 protein_coding
  ENSMUST00000096198 Scn8a-202 100933429-100940798 protein_coding
  ENSMUST00000108908 Scn8a-203 100955398-101045929 protein_coding
  ENSMUST00000108909 Scn8a-204 100955398-101045929 protein_coding
  ENSMUST00000108910 Scn8a-205 100936271-101045929 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENSMUST00000082209ENSMUST00000096198ENSMUST00000108908ENSMUST00000108909ENSMUST00000108910
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENSMUST00000082209 0.056±0.00 N/A N/A 1.675±0.00 0.074±0.00 N/A N/A 0.033±0.00 0.112±0.00 N/A N/A 0.101±0.02 0.064±0.00
ENSMUST00000096198 0.129±0.01 N/A 0.120±0.00 N/A 0.483±0.04 0.057±0.00 0.027±0.00 0.150±0.08 N/A N/A N/A 0.453±0.28 0.326±0.16
ENSMUST00000108908 N/A 0.147±0.00 N/A 5.674±0.00 N/A 0.041±0.00 0.014±0.01 0.037±0.00 0.021±0.01 N/A 0.010±0.00 0.067±0.04 N/A
ENSMUST00000108909 N/A N/A 0.028±0.00 3.633±1.92 0.217±0.00 0.084±0.00 N/A N/A 0.020±0.01 0.048±0.00 N/A 0.106±0.02 0.199±0.00
ENSMUST00000108910 N/A 0.140±0.03 N/A 14.224±0.00 N/A N/A N/A 0.047±0.00 N/A N/A N/A 0.051±0.00 0.058±0.02

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006JW CIL_0006JW_0002 CGP 15:100761747-101045929

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001518 IEA voltage-gated sodium channel complex
GO:0005248 IEA voltage-gated sodium channel activity
GO:0005886 IBA plasma membrane
GO:0007517 IMP muscle organ development
GO:0007605 IMP sensory perception of sound
GO:0007626 IMP locomotory behavior
GO:0007628 IMP adult walking behavior
GO:0008344 IMP adult locomotory behavior
GO:0009636 IDA response to toxic substance
GO:0016020 IDA membrane
GO:0019228 IBA neuronal action potential
GO:0030425 IDA dendrite
GO:0034706 IPI sodium channel complex
GO:0034765 IEA regulation of ion transmembrane transport
GO:0035725 IEA sodium ion transmembrane transport
GO:0043025 IDA neuronal cell body
GO:0050905 IMP neuromuscular process
GO:0086010 IBA membrane depolarization during action potential

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000005775 scn8aa sodium channel, voltage-gated, type VIII, alpha a protein_coding Danio_rerio
ENSDARG00000018032 scn8ab sodium channel, voltage-gated, type VIII, alpha b protein_coding Danio_rerio
ENSG00000196876 SCN8A sodium channel, voltage gated, type VIII, alpha subunit protein_coding Homo_sapiens

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