C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cystathionine beta-synthase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000024039 Cbs 10090 - 17:31612623-31637199 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000067801 Cbs-001 31612623-31637199 protein_coding
  ENSMUST00000078509 Cbs-002 31612641-31637165 protein_coding
  ENSMUST00000118504 Cbs-003 31612640-31637165 protein_coding
  ENSMUST00000128351 Cbs-006 31620947-31626188 processed_transcript
  ENSMUST00000135425 Cbs-005 31625131-31636649 protein_coding
  ENSMUST00000143982 Cbs-007 31621472-31623058 processed_transcript
  ENSMUST00000151597 Cbs-008 31617165-31617873 retained_intron
  ENSMUST00000151718 Cbs-009 31627525-31636649 protein_coding
  ENSMUST00000155814 Cbs-004 31625077-31636790 protein_coding

Mus musculus EnsemblGRCm38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000067801ENSMUST00000078509ENSMUST00000118504ENSMUST00000128351ENSMUST00000135425ENSMUST00000151597ENSMUST00000155814
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000067801 1.320±0.21 0.318±0.21 N/A 1.119±0.97 0.634±0.04 14.974±3.47 0.156±0.08 21.062±2.95 115.893±91.14 0.791±0.21 0.065±0.03 23.266±10.85 0.267±0.17 0.746±0.25
ENSMUST00000078509 2.381±1.14 0.336±0.11 0.361±0.08 1.213±0.47 1.224±0.47 12.086±4.63 0.118±0.01 30.398±11.46 84.126±77.45 1.222±0.37 0.060±0.05 47.489±8.86 0.130±0.07 0.828±0.83
ENSMUST00000118504 0.739±0.00 0.119±0.00 0.089±0.00 N/A 0.558±0.00 5.131±1.31 0.145±0.00 6.275±0.62 21.914±20.33 0.457±0.00 0.040±0.01 10.649±0.47 0.097±0.03 0.481±0.38
ENSMUST00000128351 N/A N/A N/A 17.711±0.00 N/A N/A 0.307±0.09 N/A N/A N/A N/A 62.377±0.00 0.481±0.20 0.161±0.00
ENSMUST00000135425 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.061±0.03 N/A N/A N/A
ENSMUST00000151597 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.123±0.01 N/A 0.166±0.00 N/A
ENSMUST00000155814 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.052±0.03 16.102±0.00 0.258±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008QJ CIL_0008QJ_0002 VISTA 17:31053737-31653776
CIL_0000D3 CIL_0000D3_0002 CGP 17:31564749-31637199
CIL_0000MQ CIL_0000MQ_0004 CGP 17:31612623-31658754

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001958 IMP endochondral ossification
GO:0001974 IMP blood vessel remodeling
GO:0004122 IMP cystathionine beta-synthase activity
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0006535 IEA cysteine biosynthetic process from serine
GO:0006801 IMP superoxide metabolic process
GO:0019343 IEA cysteine biosynthetic process via cystathionine
GO:0019344 IMP cysteine biosynthetic process
GO:0019346 IEA transsulfuration
GO:0021587 IMP cerebellum morphogenesis
GO:0030554 IEA adenyl nucleotide binding
GO:0030823 IMP regulation of cGMP metabolic process
GO:0031667 IEA response to nutrient levels
GO:0043066 IEA negative regulation of apoptotic process
GO:0043506 IMP regulation of JUN kinase activity
GO:0046872 IEA metal ion binding
GO:0050667 IMP homocysteine metabolic process
GO:0050880 IMP regulation of blood vessel size
GO:0051593 IMP response to folic acid
GO:0060135 IMP maternal process involved in female pregnancy
GO:0060351 IMP cartilage development involved in endochondral bone morphogenesis
GO:0070814 ISS hydrogen sulfide biosynthetic process
GO:0071456 IEA cellular response to hypoxia

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000010946 cbsb cystathionine-beta-synthase b protein_coding Danio_rerio
ENSDARG00000053500 cbsa cystathionine-beta-synthase a protein_coding Danio_rerio
ENSG00000160200 CBS cystathionine-beta-synthase protein_coding Homo_sapiens
ENSG00000274276 CBS cystathionine-beta-synthase protein_coding Homo_sapiens

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