C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: lysyl oxidase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000024529 Lox 10090 - 18:52516069-52529867 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000025409 Lox-201 52517238-52529708 protein_coding
  ENSMUST00000171470 Lox-202 52516069-52529867 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000025409ENSMUST00000171470
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000025409 26.955±5.98 6.732±1.05 2.560±0.38 1.321±1.38 21.342±10.84 5.577±1.23 1.166±0.42 2.643±1.06 0.360±0.30 24.982±8.98 N/A 26.646±12.14 1.524±0.99 0.321±0.20
ENSMUST00000171470 4.947±0.00 N/A 1.997±0.75 0.487±0.47 N/A 0.663±0.00 N/A 0.411±0.14 0.639±0.58 N/A 0.750±0.36 4.116±1.61 1.425±0.88 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004B2 CIL_0004B2_0002 CGP 18:52465693-52529867
CIL_0004B1 CIL_0004B1_0002 CGP 18:52516069-52639830

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001568 IMP blood vessel development
GO:0004720 IDA protein-lysine 6-oxidase activity
GO:0005515 IPI protein binding
GO:0005578 IDA proteinaceous extracellular matrix
GO:0005581 IDA collagen trimer
GO:0005634 IEA nucleus
GO:0009725 IEA response to hormone
GO:0030199 IMP collagen fibril organization
GO:0030324 IMP lung development
GO:0042060 IEA wound healing
GO:0042493 IEA response to drug
GO:0048251 IMP elastic fiber assembly
GO:0048545 IEA response to steroid hormone
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003259 lox lysyl oxidase protein_coding Danio_rerio
ENSDARG00000028412 LOX (2 of 2) lysyl oxidase protein_coding Danio_rerio
ENSG00000113083 LOX lysyl oxidase protein_coding Homo_sapiens

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