C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: lamin B1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000024590 Lmnb1 10090 + 18:56707813-56753424 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000025486 Lmnb1-001 56707813-56753424 protein_coding
  ENSMUST00000128651 Lmnb1-002 56728441-56733456 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000025486ENSMUST00000128651
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000025486 3.379±2.28 1.715±0.36 4.695±0.36 27.412±17.86 3.364±2.19 4.643±0.98 0.448±0.25 0.947±0.36 15.772±17.80 2.449±0.72 2.129±0.27 15.411±7.08 41.696±30.09 3.329±0.37
ENSMUST00000128651 N/A N/A N/A 8.668±0.00 N/A N/A N/A N/A N/A N/A N/A 80.034±0.00 194.823±165.20 26.795±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00041Q CIL_00041Q_0002 CGP 18:56588350-56753424
CIL_0007S2 CIL_0007S2_0002 VISTA 18:56596918-57198991
CIL_00041J CIL_00041J_0002 CGP 18:56707813-56925548

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005198 IEA structural molecule activity
GO:0005634 IDA nucleus
GO:0005635 IDA nuclear envelope
GO:0005637 IEA nuclear inner membrane
GO:0005638 IDA lamin filament
GO:0005654 IDA nucleoplasm
GO:0008432 NAS JUN kinase binding
GO:0016020 IEA membrane
GO:0031662 NAS positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle
GO:0031965 IEA nuclear membrane
GO:0043274 IPI phospholipase binding
GO:0046330 NAS positive regulation of JNK cascade

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000044299 lmnb1 lamin B1 protein_coding Danio_rerio
ENSG00000113368 LMNB1 lamin B1 protein_coding Homo_sapiens

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