C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: lamin B1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000113368 LMNB1 9606 + 5:126776623-126837020 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000261366 LMNB1-001 126777148-126837020 protein_coding
  ENST00000395354 LMNB1-003 126777189-126819234 protein_coding
  ENST00000460265 LMNB1-002 126776623-126837014 processed_transcript
  ENST00000463908 LMNB1-006 126777379-126810255 processed_transcript
  ENST00000472034 LMNB1-004 126777161-126818979 processed_transcript
  ENST00000492190 LMNB1-005 126777161-126804914 processed_transcript
  ENST00000494185 LMNB1-007 126811713-126821081 retained_intron
  ENST00000504788 LMNB1-009 126777153-126836571 processed_transcript
  ENST00000512460 LMNB1-011 126818928-126826109 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000261366ENST00000395354ENST00000460265ENST00000463908ENST00000472034ENST00000492190ENST00000494185ENST00000504788ENST00000512460
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000261366 1.274±0.00 3.110±0.00 0.235±0.00 0.793±0.68 1.366±0.03 3.706±1.20 0.492±0.00 0.528±0.00 1.356±0.00 2.749±2.35 N/A 4.414±3.65 6.594±2.68 2.181±0.00
ENST00000395354 N/A N/A N/A N/A 1.082±0.00 N/A N/A 0.481±0.00 N/A N/A 0.337±0.00 1.732±0.00 N/A N/A
ENST00000460265 N/A N/A N/A 0.183±0.00 N/A N/A N/A N/A N/A N/A N/A 1.220±0.00 N/A N/A
ENST00000463908 N/A N/A N/A N/A N/A N/A 0.336±0.00 N/A 2.322±0.00 1.581±0.00 N/A N/A N/A N/A
ENST00000472034 N/A N/A 0.421±0.00 N/A N/A N/A N/A 2.200±0.00 N/A N/A N/A N/A N/A N/A
ENST00000492190 N/A N/A 0.952±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000494185 N/A N/A N/A N/A N/A N/A 0.257±0.00 1.247±0.00 N/A N/A 0.688±0.00 N/A N/A 8.084±0.00
ENST00000504788 1.310±0.00 2.680±0.00 N/A 0.731±0.06 3.702±0.00 2.648±2.06 0.081±0.00 0.819±0.00 N/A 1.752±0.49 0.096±0.00 5.061±2.92 3.187±2.50 3.751±0.26
ENST00000512460 N/A 3.472±0.00 0.445±0.00 2.040±0.00 N/A N/A N/A N/A 0.877±0.00 N/A N/A 20.282±0.00 18.285±0.00 8.837±1.90

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00041Q CIL_00041Q_0001 CGP 5:126631722-126837020
CIL_0007S2 CIL_0007S2_0001 VISTA 5:126699007-127301374
CIL_00041J CIL_00041J_0001 CGP 5:126776623-127030808

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005198 IEA structural molecule activity
GO:0005634 IEA nucleus
GO:0005635 TAS nuclear envelope
GO:0005637 IEA nuclear inner membrane
GO:0005638 IEA lamin filament
GO:0005654 TAS nucleoplasm
GO:0005882 IEA intermediate filament
GO:0006915 TAS apoptotic process
GO:0006921 TAS cellular component disassembly involved in execution phase of apoptosis
GO:0016020 IDA membrane
GO:0031965 IDA nuclear membrane
GO:0043274 IEA phospholipase binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000044299 lmnb1 lamin B1 protein_coding Danio_rerio
ENSMUSG00000024590 Lmnb1 lamin B1 protein_coding Mus_musculus

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