C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glial cell line derived neurotrophic factor family receptor alpha 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025089 Gfra1 10090 - 19:58235604-58455909 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000026076 Gfra1-001 58235604-58455398 protein_coding
  ENSMUST00000123957 Gfra1-008 58453421-58454620 protein_coding
  ENSMUST00000129100 Gfra1-004 58235612-58454592 protein_coding
  ENSMUST00000131877 Gfra1-005 58453352-58455909 protein_coding
  ENSMUST00000135730 Gfra1-006 58454324-58455161 protein_coding
  ENSMUST00000138530 Gfra1-007 58453335-58455006 protein_coding
  ENSMUST00000140141 Gfra1-003 58238162-58455359 nonsense_mediated_decay
  ENSMUST00000152507 Gfra1-002 58238162-58455301 protein_coding
  ENSMUST00000169850 Gfra1-201 58236692-58454466 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000026076ENSMUST00000123957ENSMUST00000129100ENSMUST00000131877ENSMUST00000140141ENSMUST00000152507ENSMUST00000169850
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000026076 N/A N/A 0.481±0.07 5.284±3.24 0.114±0.00 0.198±0.00 0.232±0.09 0.359±0.04 0.994±0.43 0.583±0.21 0.151±0.03 0.305±0.00 0.028±0.00 0.276±0.00
ENSMUST00000123957 N/A 0.585±0.10 N/A N/A 1.054±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000129100 0.219±0.12 0.155±0.08 0.937±0.12 4.660±0.00 0.486±0.26 0.322±0.05 0.561±0.23 1.224±0.47 3.285±2.18 1.203±0.00 0.540±0.20 0.373±0.31 0.028±0.01 0.699±0.32
ENSMUST00000131877 N/A N/A N/A N/A N/A 0.778±0.08 N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000140141 N/A N/A N/A N/A N/A 0.416±0.00 N/A N/A N/A N/A N/A 0.491±0.07 N/A N/A
ENSMUST00000152507 N/A 0.292±0.17 N/A N/A 0.242±0.04 0.550±0.16 N/A 1.115±0.00 N/A 0.623±0.00 N/A 1.868±0.00 0.066±0.00 N/A
ENSMUST00000169850 0.346±0.12 0.152±0.10 0.279±0.00 3.708±2.73 0.549±0.18 0.532±0.16 0.743±0.27 0.931±0.44 3.992±3.10 1.755±0.40 0.114±0.00 1.157±0.67 0.038±0.02 0.187±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006S7 CIL_0006S7_0002 CGP 19:57611034-58455909
CIL_00088K CIL_00088K_0002 VISTA 19:58071922-58673062
CIL_0008H3 CIL_0008H3_0002 VISTA 19:58119231-58720471
CIL_0006FD CIL_0006FD_0003 CGP 19:58235604-58553085

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004872 TAS receptor activity
GO:0005886 IEA plasma membrane
GO:0007169 TAS transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007399 IMP nervous system development
GO:0009653 TAS anatomical structure morphogenesis
GO:0019898 TAS extrinsic component of membrane
GO:0031225 IEA anchored component of membrane
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000013975 gfra1b gdnf family receptor alpha 1b protein_coding Danio_rerio
ENSDARG00000039936 GFRA1 (2 of 3) GDNF family receptor alpha 1 protein_coding Danio_rerio
ENSDARG00000058513 gfra1a gdnf family receptor alpha 1a protein_coding Danio_rerio
ENSG00000151892 GFRA1 GDNF family receptor alpha 1 protein_coding Homo_sapiens

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