C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: LIM domain binding 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025223 Ldb1 10090 - 19:46032593-46045214 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000026252 Ldb1-001 46032689-46044914 protein_coding
  ENSMUST00000056931 Ldb1-003 46032594-46039621 protein_coding
  ENSMUST00000126320 Ldb1-006 46033745-46034878 retained_intron
  ENSMUST00000136203 Ldb1-005 46034051-46036000 retained_intron
  ENSMUST00000137771 Ldb1-004 46033425-46039481 protein_coding
  ENSMUST00000152946 Ldb1-002 46032593-46045214 protein_coding
  ENSMUST00000156585 Ldb1-007 46032689-46045210 protein_coding
  ENSMUST00000185355 Ldb1-201 46032616-46045211 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000026252ENSMUST00000137771ENSMUST00000152946ENSMUST00000156585ENSMUST00000185355
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000026252 41.171±0.41 18.032±1.65 53.537±2.32 97.266±15.79 47.549±7.38 19.875±2.59 17.169±3.21 23.847±1.99 37.589±35.23 53.259±6.01 6.341±1.06 48.170±22.93 57.838±36.90 5.523±1.22
ENSMUST00000137771 16.324±0.42 N/A 23.222±0.00 44.916±7.55 35.436±20.15 N/A N/A N/A 47.848±17.16 N/A 3.400±0.23 36.501±11.40 19.291±7.33 1.097±0.00
ENSMUST00000152946 22.692±5.41 12.267±3.32 25.472±0.41 26.011±0.76 21.104±2.34 13.222±1.77 8.097±0.27 9.890±1.40 11.986±8.86 20.067±4.46 4.011±0.72 25.104±6.28 13.572±6.43 2.412±0.00
ENSMUST00000156585 N/A 13.155±1.74 N/A N/A N/A 15.867±0.00 10.540±0.00 N/A N/A N/A N/A 45.056±0.00 N/A N/A
ENSMUST00000185355 27.000±0.00 10.210±1.13 N/A N/A N/A 20.257±0.00 N/A N/A N/A N/A 5.415±1.62 37.787±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00099F CIL_00099F_0002 VISTA 19:45434459-46035623
CIL_00099E CIL_00099E_0002 VISTA 19:45446900-46047683
CIL_0005WD CIL_0005WD_0002 CGP 19:46003478-46045214
CIL_00058F CIL_00058F_0002 CGP 19:46032593-46072915

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000790 IEA nuclear chromatin
GO:0000972 IMP transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
GO:0000989 IPI transcription factor binding transcription factor activity
GO:0001102 IEA RNA polymerase II activating transcription factor binding
GO:0001158 IDA enhancer sequence-specific DNA binding
GO:0001702 IMP gastrulation with mouth forming second
GO:0001942 IGI hair follicle development
GO:0003677 IDA DNA binding
GO:0003682 IDA chromatin binding
GO:0003712 IEA transcription cofactor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005667 IEA transcription factor complex
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0009948 IMP anterior/posterior axis specification
GO:0010669 IGI epithelial structure maintenance
GO:0016055 IMP Wnt signaling pathway
GO:0019899 IPI enzyme binding
GO:0021549 IMP cerebellum development
GO:0021702 IMP cerebellar Purkinje cell differentiation
GO:0022607 IGI cellular component assembly
GO:0030182 IEP neuron differentiation
GO:0030274 IDA LIM domain binding
GO:0032784 IMP regulation of DNA-templated transcription, elongation
GO:0035019 IGI somatic stem cell maintenance
GO:0042803 IDA protein homodimerization activity
GO:0043234 IDA protein complex
GO:0043621 IPI protein self-association
GO:0043973 IMP histone H3-K4 acetylation
GO:0045647 IMP negative regulation of erythrocyte differentiation
GO:0045785 IGI positive regulation of cell adhesion
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0046985 IMP positive regulation of hemoglobin biosynthetic process
GO:0060319 TAS primitive erythrocyte differentiation
GO:0060322 IGI head development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000010137 ldb1a LIM-domain binding factor 1a protein_coding Danio_rerio
ENSG00000198728 LDB1 LIM domain binding 1 protein_coding Homo_sapiens

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