C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: LIM domain binding 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000198728 LDB1 9606 - 10:102107560-102120453 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000361198 LDB1-001 102107560-102114946 protein_coding
  ENST00000425280 LDB1-201 102107583-102120453 protein_coding
  ENST00000461873 LDB1-002 102110392-102111133 processed_transcript
  ENST00000490751 LDB1-003 102110630-102120448 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000361198ENST00000425280ENST00000490751
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000361198 N/A N/A N/A 1.983±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000425280 7.105±0.00 4.315±0.00 7.429±0.00 N/A 4.488±0.00 4.550±1.23 2.706±0.00 4.443±0.00 3.569±0.00 1.631±0.00 21.501±13.20 8.946±1.88 4.461±0.00
ENST00000490751 N/A N/A N/A 3.238±0.00 N/A N/A 4.064±0.00 N/A 5.249±0.00 N/A 19.218±0.00 17.802±0.00 15.198±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005WD CIL_0005WD_0001 CGP 10:102065390-102120453
CIL_00058F CIL_00058F_0001 CGP 10:102107560-102150331

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000790 IDA nuclear chromatin
GO:0000972 ISS transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
GO:0000989 IEA transcription factor binding transcription factor activity
GO:0001102 IPI RNA polymerase II activating transcription factor binding
GO:0001158 IEA enhancer sequence-specific DNA binding
GO:0001702 IEA gastrulation with mouth forming second
GO:0001942 IEA hair follicle development
GO:0003677 IEA DNA binding
GO:0003682 IEA chromatin binding
GO:0003714 TAS transcription corepressor activity
GO:0005515 IEA protein binding
GO:0005634 ISS nucleus
GO:0005667 IDA transcription factor complex
GO:0006351 NAS transcription, DNA-templated
GO:0006355 NAS regulation of transcription, DNA-templated
GO:0006366 IEA transcription from RNA polymerase II promoter
GO:0007275 NAS multicellular organismal development
GO:0009948 IEA anterior/posterior axis specification
GO:0010669 IEA epithelial structure maintenance
GO:0016055 IEA Wnt signaling pathway
GO:0019899 IPI enzyme binding
GO:0021549 IEA cerebellum development
GO:0021702 IEA cerebellar Purkinje cell differentiation
GO:0022607 IEA cellular component assembly
GO:0030182 ISS neuron differentiation
GO:0030274 ISS LIM domain binding
GO:0032784 ISS regulation of DNA-templated transcription, elongation
GO:0035019 IEA somatic stem cell maintenance
GO:0042803 ISS protein homodimerization activity
GO:0043234 ISS protein complex
GO:0043621 IEA protein self-association
GO:0043973 ISS histone H3-K4 acetylation
GO:0045647 ISS negative regulation of erythrocyte differentiation
GO:0045785 IEA positive regulation of cell adhesion
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0046985 ISS positive regulation of hemoglobin biosynthetic process
GO:0060322 IEA head development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000010137 ldb1a LIM-domain binding factor 1a protein_coding Danio_rerio
ENSMUSG00000025223 Ldb1 LIM domain binding 1 protein_coding Mus_musculus

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