C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: CDC42 guanine nucleotide exchange factor (GEF) 9
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025656 Arhgef9 10090 - X:95048935-95196821 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000113873 Arhgef9-004 95051926-95166307 protein_coding
  ENSMUST00000113876 Arhgef9-001 95048935-95166361 protein_coding
  ENSMUST00000113878 Arhgef9-201 95048944-95166486 protein_coding
  ENSMUST00000113882 Arhgef9-002 95048944-95166486 protein_coding
  ENSMUST00000113883 Arhgef9-003 95048939-95166406 protein_coding
  ENSMUST00000113884 Arhgef9-007 95050266-95196821 protein_coding
  ENSMUST00000113885 Arhgef9-005 95048938-95166373 protein_coding
  ENSMUST00000128565 Arhgef9-006 95050266-95196821 nonsense_mediated_decay
  ENSMUST00000181987 Arhgef9-008 95051919-95196505 protein_coding
  ENSMUST00000182001 Arhgef9-009 95048944-95166474 protein_coding
  ENSMUST00000182135 Arhgef9-012 95051919-95052792 processed_transcript
  ENSMUST00000182137 Arhgef9-011 95051920-95058953 protein_coding
  ENSMUST00000182562 Arhgef9-010 95101050-95166539 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000113873ENSMUST00000113876ENSMUST00000113878ENSMUST00000113882ENSMUST00000113883ENSMUST00000113884ENSMUST00000113885ENSMUST00000128565ENSMUST00000181987ENSMUST00000182001ENSMUST00000182137
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000113873 1.191±0.11 N/A N/A 31.135±0.00 0.870±0.34 N/A N/A 0.560±0.15 0.311±0.08 N/A N/A 1.533±0.00 0.145±0.06 N/A
ENSMUST00000113876 1.050±0.36 N/A 0.834±0.05 3.958±2.22 0.675±0.11 N/A 0.898±0.11 0.462±0.09 0.245±0.16 0.281±0.00 1.081±0.59 0.874±0.00 0.037±0.00 0.091±0.02
ENSMUST00000113878 N/A 0.333±0.00 N/A N/A 0.334±0.00 N/A N/A N/A N/A N/A 0.450±0.00 N/A N/A N/A
ENSMUST00000113882 N/A 0.413±0.05 N/A N/A 0.377±0.05 N/A N/A 0.568±0.00 N/A N/A N/A N/A N/A N/A
ENSMUST00000113883 0.600±0.24 0.638±0.00 2.175±0.18 2.823±0.11 0.897±0.42 0.456±0.00 1.033±0.32 0.276±0.11 0.165±0.04 0.866±0.05 0.515±0.00 0.789±0.27 0.071±0.03 0.047±0.00
ENSMUST00000113884 N/A 0.470±0.12 N/A 14.361±0.00 0.311±0.00 0.488±0.08 N/A N/A N/A 0.296±0.00 N/A 0.693±0.13 0.116±0.02 0.062±0.02
ENSMUST00000113885 N/A N/A N/A N/A 0.538±0.00 N/A 0.712±0.00 0.149±0.00 0.131±0.00 N/A 0.691±0.13 0.429±0.00 0.046±0.00 0.068±0.03
ENSMUST00000128565 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.013±0.00
ENSMUST00000181987 N/A N/A 1.325±0.13 4.967±0.13 0.331±0.00 N/A N/A N/A 0.247±0.13 0.378±0.00 N/A 0.500±0.10 0.086±0.04 0.055±0.00
ENSMUST00000182001 0.411±0.00 N/A N/A 7.209±2.67 0.306±0.00 N/A N/A N/A 0.341±0.23 N/A N/A 0.583±0.15 N/A 0.022±0.00
ENSMUST00000182137 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.513±0.01 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002RM CIL_0002RM_0002 CGP X:95022510-95196821
CIL_0003JJ CIL_0003JJ_0003 CGP X:95048935-95444872

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005085 TAS guanyl-nucleotide exchange factor activity
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005938 TAS cell cortex
GO:0007264 TAS small GTPase mediated signal transduction
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0043547 TAS positive regulation of GTPase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000061746 arhgef9a Cdc42 guanine nucleotide exchange factor (GEF) 9a protein_coding Danio_rerio
ENSDARG00000076601 arhgef9b Cdc42 guanine nucleotide exchange factor (GEF) 9b protein_coding Danio_rerio
ENSDARG00000078624 arhgef9b Cdc42 guanine nucleotide exchange factor (GEF) 9b protein_coding Danio_rerio
ENSG00000131089 ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9 protein_coding Homo_sapiens

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