C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: HGF-regulated tyrosine kinase substrate
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025793 Hgs 10090 + 11:120467635-120483984 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000026900 Hgs-201 120467635-120483984 protein_coding
  ENSMUST00000106203 Hgs-002 120467635-120483979 protein_coding
  ENSMUST00000106205 Hgs-001 120467635-120483979 protein_coding
  ENSMUST00000135231 Hgs-005 120477515-120480187 protein_coding
  ENSMUST00000140862 Hgs-004 120467635-120477332 protein_coding
  ENSMUST00000141826 Hgs-003 120467635-120475319 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000026900ENSMUST00000106205ENSMUST00000135231ENSMUST00000141826
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000026900 14.198±4.83 50.449±4.42 9.335±4.23 36.757±4.91 19.344±10.35 35.701±6.97 4.891±3.71 16.917±2.92 12.159±6.71 23.156±4.03 1.984±0.77 36.386±16.46 8.369±3.13 56.844±20.67
ENSMUST00000106205 8.164±2.11 13.157±1.48 2.911±0.00 9.699±2.00 8.028±2.05 11.938±3.87 4.089±0.12 8.900±1.11 5.523±2.19 9.229±1.19 2.827±0.27 10.966±2.58 8.011±2.45 28.776±9.37
ENSMUST00000135231 N/A N/A N/A 59.871±0.00 N/A N/A N/A N/A N/A N/A N/A 69.933±0.00 52.891±1.72 104.704±0.00
ENSMUST00000141826 N/A N/A N/A 34.981±0.00 N/A N/A N/A N/A N/A N/A N/A 8.141±0.00 44.869±0.00 59.315±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003BA CIL_0003BA_0002 CGP 11:120464866-120483984
CIL_0004BU CIL_0004BU_0002 CGP 11:120467635-120489065

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IEA protein binding
GO:0005737 IDA cytoplasm
GO:0005768 IEA endosome
GO:0005769 IEA early endosome
GO:0005829 IEA cytosol
GO:0006622 IEA protein targeting to lysosome
GO:0006886 IEA intracellular protein transport
GO:0008333 IEA endosome to lysosome transport
GO:0010324 IEA membrane invagination
GO:0010628 IEA positive regulation of gene expression
GO:0016020 IEA membrane
GO:0019904 IEA protein domain specific binding
GO:0030141 IEA secretory granule
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0046426 IEA negative regulation of JAK-STAT cascade
GO:0046872 IEA metal ion binding
GO:0070062 IEA extracellular vesicular exosome
GO:0072657 IEA protein localization to membrane

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020960 hgs hepatocyte growth factor-regulated tyrosine kinase substrate protein_coding Danio_rerio
ENSG00000185359 HGS hepatocyte growth factor-regulated tyrosine kinase substrate protein_coding Homo_sapiens

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