C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: IscU iron-sulfur cluster scaffold homolog (E. coli)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025825 Iscu 10090 + 5:113772748-113778288 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000026937 Iscu-001 113772748-113778288 protein_coding
  ENSMUST00000112311 Iscu-002 113772803-113777798 protein_coding
  ENSMUST00000112312 Iscu-003 113772803-113778273 protein_coding
  ENSMUST00000123616 Iscu-004 113772818-113777039 nonsense_mediated_decay
  ENSMUST00000134881 Iscu-005 113773025-113777945 nonsense_mediated_decay
  ENSMUST00000145592 Iscu-007 113773847-113777841 protein_coding
  ENSMUST00000145778 Iscu-006 113773005-113778014 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000026937ENSMUST00000112311ENSMUST00000112312ENSMUST00000123616ENSMUST00000134881ENSMUST00000145592
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000026937 113.896±31.23 218.038±23.65 111.743±12.87 38.933±16.53 67.817±17.98 38.105±4.08 89.922±6.43 206.075±10.11 62.752±9.22 71.473±11.00 79.129±3.71 73.396±15.73 44.529±5.33 68.155±16.15
ENSMUST00000112311 N/A N/A N/A 3.162±0.08 5.605±1.17 4.003±0.19 N/A N/A 5.537±0.00 N/A N/A 8.620±2.22 N/A N/A
ENSMUST00000112312 N/A 43.537±4.66 N/A N/A 6.367±0.58 7.115±1.31 N/A 17.428±0.00 7.547±0.00 7.323±0.00 N/A 8.776±2.12 N/A N/A
ENSMUST00000123616 N/A 37.150±11.09 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000134881 N/A N/A N/A 22.094±0.00 N/A N/A N/A N/A N/A N/A N/A 25.887±0.00 N/A N/A
ENSMUST00000145592 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 51.666±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001M7 CIL_0001M7_0002 CGP 5:113742446-113778288
CIL_0007IZ CIL_0007IZ_0003 CGP 5:113772748-113800516

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005506 IEA iron ion binding
GO:0005515 IEA protein binding
GO:0005737 IEA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005829 IEA cytosol
GO:0016226 IEA iron-sulfur cluster assembly
GO:0032947 IEA protein complex scaffold
GO:0051536 IEA iron-sulfur cluster binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000026582 iscub iron-sulfur cluster scaffold homolog (E. coli) b protein_coding Danio_rerio
ENSDARG00000035596 ISCU (2 of 2) iron-sulfur cluster assembly enzyme protein_coding Danio_rerio
ENSG00000136003 ISCU iron-sulfur cluster assembly enzyme protein_coding Homo_sapiens

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