C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: WW domain containing transcription regulator 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000027803 Wwtr1 10090 - 3:57455649-57575910 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000029380 Wwtr1-001 57455649-57575828 protein_coding
  ENSMUST00000120977 Wwtr1-002 57455782-57575910 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000029380ENSMUST00000120977
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000029380 41.851±7.57 29.966±4.88 30.841±0.57 5.478±3.77 27.350±9.93 15.169±0.85 16.835±1.72 19.584±2.52 3.096±1.17 50.930±7.01 4.964±0.55 42.308±17.47 17.283±12.00 2.517±1.90
ENSMUST00000120977 N/A N/A N/A 1.007±0.00 N/A N/A N/A N/A N/A N/A N/A 10.889±2.72 13.299±2.30 3.224±1.84

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002R1 CIL_0002R1_0002 CGP 3:57425314-57575910
CIL_0002R8 CIL_0002R8_0002 CGP 3:57455649-57651715

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IGI negative regulation of transcription from RNA polymerase II promoter
GO:0001649 IGI osteoblast differentiation
GO:0001933 IEA negative regulation of protein phosphorylation
GO:0003713 IDA transcription coactivator activity
GO:0003714 IGI transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005667 IDA transcription factor complex
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0006469 IEA negative regulation of protein kinase activity
GO:0008284 IEA positive regulation of cell proliferation
GO:0010718 IEA positive regulation of epithelial to mesenchymal transition
GO:0016567 IDA protein ubiquitination
GO:0017145 IEA stem cell division
GO:0031146 IMP SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0032835 IMP glomerulus development
GO:0035264 IMP multicellular organism growth
GO:0035329 IEA hippo signaling
GO:0035414 IEA negative regulation of catenin import into nucleus
GO:0042803 IDA protein homodimerization activity
GO:0045599 IGI negative regulation of fat cell differentiation
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048762 IMP mesenchymal cell differentiation
GO:0060271 IMP cilium morphogenesis
GO:0060390 IEA regulation of SMAD protein import into nucleus
GO:0060828 IGI regulation of canonical Wnt signaling pathway
GO:0060993 IMP kidney morphogenesis
GO:0072307 IGI regulation of metanephric nephron tubule epithelial cell differentiation
GO:0090090 IEA negative regulation of canonical Wnt signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000067719 wwtr1 WW domain containing transcription regulator 1 protein_coding Danio_rerio
ENSG00000018408 WWTR1 WW domain containing transcription regulator 1 protein_coding Homo_sapiens

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