C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: WW domain containing transcription regulator 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000120977 Wwtr1-002 ENSMUSG00000027803 10090 - 3:57455782-57575910 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainOvaryPlacentaTestisENSMUST00000120977
Transcript ID Brain Ovary Placenta Testis
ENSMUST00000120977 1.007±0.00 10.889±2.72 13.299±2.30 3.224±1.84

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002R1 CIL_0002R1_0002 CGP 3:57425314-57575910
CIL_0002R8 CIL_0002R8_0002 CGP 3:57455649-57651715

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IGI negative regulation of transcription from RNA polymerase II promoter
GO:0001649 IGI osteoblast differentiation
GO:0001933 IEA negative regulation of protein phosphorylation
GO:0003713 IDA transcription coactivator activity
GO:0003714 IGI transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005667 IDA transcription factor complex
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0006469 IEA negative regulation of protein kinase activity
GO:0008284 IEA positive regulation of cell proliferation
GO:0010718 IEA positive regulation of epithelial to mesenchymal transition
GO:0016567 IDA protein ubiquitination
GO:0017145 IEA stem cell division
GO:0031146 IMP SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0032835 IMP glomerulus development
GO:0035264 IMP multicellular organism growth
GO:0035329 IEA hippo signaling
GO:0035414 IEA negative regulation of catenin import into nucleus
GO:0042803 IDA protein homodimerization activity
GO:0045599 IGI negative regulation of fat cell differentiation
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048762 IMP mesenchymal cell differentiation
GO:0060271 IMP cilium morphogenesis
GO:0060390 IEA regulation of SMAD protein import into nucleus
GO:0060828 IGI regulation of canonical Wnt signaling pathway
GO:0060993 IMP kidney morphogenesis
GO:0072307 IGI regulation of metanephric nephron tubule epithelial cell differentiation
GO:0090090 IEA negative regulation of canonical Wnt signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000360632 WWTR1-004 protein_coding Homo_sapiens 0 1602
ENST00000465804 WWTR1-001 protein_coding Homo_sapiens 0 1648
ENST00000467467 WWTR1-003 protein_coding Homo_sapiens 0 1482
ENST00000471586 WWTR1-012 nonsense_mediated_decay Homo_sapiens 0 496
ENST00000472417 WWTR1-010 protein_coding Homo_sapiens 0 819
ENST00000475579 WWTR1-006 protein_coding Homo_sapiens 0 425
ENST00000479238 WWTR1-009 protein_coding Homo_sapiens 0 734
ENST00000485244 WWTR1-011 retained_intron Homo_sapiens 0 394
ENST00000485352 WWTR1-008 protein_coding Homo_sapiens 0 542
ENST00000494754 WWTR1-013 nonsense_mediated_decay Homo_sapiens 0 481

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