C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: aprataxin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000028411 Aptx 10090 - 4:40682382-40703194 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000030119 Aptx-001 40682382-40703194 protein_coding
  ENSMUST00000068125 Aptx-004 40682382-40702914 protein_coding
  ENSMUST00000108103 Aptx-003 40684924-40703162 protein_coding
  ENSMUST00000128810 Aptx-006 40691003-40694507 processed_transcript
  ENSMUST00000129021 Aptx-002 40686242-40703187 nonsense_mediated_decay
  ENSMUST00000155710 Aptx-005 40695020-40702716 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000030119ENSMUST00000068125ENSMUST00000108103ENSMUST00000129021
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000030119 0.496±0.07 N/A 1.379±0.27 1.604±0.46 0.494±0.39 0.449±0.26 0.645±0.27 0.292±0.00 0.383±0.09 0.502±0.00 1.309±0.45 0.743±0.35 0.532±0.13 N/A
ENSMUST00000068125 0.406±0.10 0.527±0.07 0.385±0.00 0.956±0.22 0.371±0.09 0.245±0.00 N/A 0.617±0.26 0.330±0.15 N/A N/A 0.920±0.56 0.688±0.29 N/A
ENSMUST00000108103 0.819±0.05 2.133±0.20 N/A N/A 1.299±0.48 1.502±0.20 0.714±0.01 0.929±0.30 0.493±0.16 1.995±0.36 N/A 2.446±0.60 0.935±0.08 N/A
ENSMUST00000129021 4.804±0.88 0.946±0.22 6.109±0.78 7.852±2.04 2.774±0.83 1.144±0.49 3.116±0.20 3.403±0.19 2.530±0.67 2.914±0.54 5.307±0.51 4.147±3.81 8.944±1.65 63.036±40.69

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000655 CIL_000655_0002 CGP 4:40472180-40703194
CIL_00061D CIL_00061D_0002 CGP 4:40682382-40737149

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000012 IMP single strand break repair
GO:0000738 IEA DNA catabolic process, exonucleolytic
GO:0000785 IEA chromatin
GO:0000790 IEA nuclear chromatin
GO:0003682 IEA chromatin binding
GO:0003684 IEA damaged DNA binding
GO:0003690 IEA double-stranded DNA binding
GO:0003725 IEA double-stranded RNA binding
GO:0005634 IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005730 IEA nucleolus
GO:0006266 IDA DNA ligation
GO:0006302 IEA double-strand break repair
GO:0006974 IEA cellular response to DNA damage stimulus
GO:0008967 IEA phosphoglycolate phosphatase activity
GO:0016311 IEA dephosphorylation
GO:0031647 IEA regulation of protein stability
GO:0033699 IMP DNA 5'-adenosine monophosphate hydrolase activity
GO:0042542 IEA response to hydrogen peroxide
GO:0046403 IEA polynucleotide 3'-phosphatase activity
GO:0046872 TAS metal ion binding
GO:0047485 IEA protein N-terminus binding
GO:0051219 IEA phosphoprotein binding
GO:0098506 IEA polynucleotide 3' dephosphorylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000027143 aptx aprataxin protein_coding Danio_rerio
ENSG00000137074 APTX aprataxin protein_coding Homo_sapiens

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