C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: aprataxin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000137074 APTX 9606 - 9:32972606-33025168 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000309615 APTX-201 32972607-33001612 protein_coding
  ENST00000379812 APTX-030 32984631-33001607 protein_coding
  ENST00000379813 APTX-202 32973396-33001612 protein_coding
  ENST00000379817 APTX-011 32972618-32990088 protein_coding
  ENST00000379819 APTX-003 32972749-33001604 protein_coding
  ENST00000379825 APTX-002 32972606-33001628 protein_coding
  ENST00000397172 APTX-021 32972616-33001607 protein_coding
  ENST00000436040 APTX-203 32972607-33001576 protein_coding
  ENST00000460940 APTX-016 32972618-32990088 nonsense_mediated_decay
  ENST00000460945 APTX-022 32987543-33025168 processed_transcript
  ENST00000463596 APTX-007 32973376-33001522 protein_coding
  ENST00000464632 APTX-018 32984659-33001619 nonsense_mediated_decay
  ENST00000465003 APTX-001 32972618-32990088 nonsense_mediated_decay
  ENST00000467331 APTX-012 32972618-32990088 nonsense_mediated_decay
  ENST00000468275 APTX-017 32973165-32997331 protein_coding
  ENST00000472896 APTX-013 32972618-32990088 nonsense_mediated_decay
  ENST00000473221 APTX-025 32984631-33001641 protein_coding
  ENST00000473270 APTX-023 33015888-33025110 processed_transcript
  ENST00000474658 APTX-028 32973242-33001579 nonsense_mediated_decay
  ENST00000476858 APTX-006 32973376-33001641 protein_coding
  ENST00000477119 APTX-026 32984772-33001612 protein_coding
  ENST00000478279 APTX-019 32984659-33001619 nonsense_mediated_decay
  ENST00000479656 APTX-004 32972763-32997360 nonsense_mediated_decay
  ENST00000480031 APTX-027 32984715-33001597 nonsense_mediated_decay
  ENST00000482687 APTX-015 32972618-32990088 nonsense_mediated_decay
  ENST00000483148 APTX-014 32972618-32990088 nonsense_mediated_decay
  ENST00000485479 APTX-010 32972618-32990088 nonsense_mediated_decay
  ENST00000486724 APTX-032 32980388-32987762 processed_transcript
  ENST00000489583 APTX-024 33019954-33024987 processed_transcript
  ENST00000494649 APTX-009 32972616-33001521 nonsense_mediated_decay
  ENST00000494973 APTX-029 32987777-33001628 retained_intron
  ENST00000495360 APTX-008 32973407-33025112 nonsense_mediated_decay
  ENST00000496030 APTX-031 32985989-32988134 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000309615ENST00000379813ENST00000379817ENST00000379819ENST00000379825ENST00000397172ENST00000460940ENST00000460945ENST00000463596ENST00000467331ENST00000468275ENST00000476858ENST00000479656ENST00000480031ENST00000482687ENST00000494649ENST00000495360ENST00000496030
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000309615 1.006±0.00 N/A 9.021±0.00 1.879±0.00 2.681±0.00 0.756±0.00 3.788±0.00 2.106±0.00 N/A N/A 3.466±0.92 1.218±0.00 N/A
ENST00000379813 N/A N/A N/A N/A N/A 0.378±0.00 N/A N/A 4.506±0.00 N/A N/A N/A N/A
ENST00000379817 N/A N/A N/A N/A N/A 0.278±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000379819 1.061±0.00 4.873±0.00 0.829±0.00 1.814±0.00 N/A 1.616±0.00 3.756±0.00 N/A N/A N/A 2.480±1.28 2.054±0.48 N/A
ENST00000379825 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.711±0.00 N/A N/A
ENST00000397172 1.005±0.00 N/A N/A 1.751±0.00 1.114±0.00 N/A N/A N/A N/A 1.892±0.00 0.938±0.00 N/A N/A
ENST00000460940 N/A N/A N/A 1.274±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000460945 N/A N/A N/A N/A N/A N/A 2.026±0.00 N/A N/A N/A N/A N/A N/A
ENST00000463596 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 9.186±0.00
ENST00000467331 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.993±0.00 N/A N/A
ENST00000468275 1.394±0.00 N/A N/A N/A N/A 1.151±0.00 N/A N/A N/A N/A 9.387±0.00 7.765±0.00 6.879±0.00
ENST00000476858 2.304±0.00 8.287±0.00 N/A N/A N/A N/A N/A N/A N/A 1.470±0.00 N/A N/A N/A
ENST00000479656 N/A N/A N/A N/A 2.450±0.00 N/A N/A 0.721±0.00 N/A N/A 5.389±0.00 1.623±0.00 6.748±0.00
ENST00000480031 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.975±0.00 N/A N/A
ENST00000482687 N/A N/A N/A N/A N/A N/A 1.815±0.00 N/A N/A N/A N/A N/A N/A
ENST00000494649 N/A N/A N/A 1.193±0.00 N/A N/A N/A 0.852±0.00 1.357±0.00 N/A N/A N/A N/A
ENST00000495360 N/A N/A 0.919±0.00 N/A 1.809±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000496030 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 9.013±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000655 CIL_000655_0001 CGP 9:32783499-33025168
CIL_00061D CIL_00061D_0001 CGP 9:32972606-33039907

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000012 IDA single strand break repair
GO:0000738 IEA DNA catabolic process, exonucleolytic
GO:0000785 IDA chromatin
GO:0000790 IDA nuclear chromatin
GO:0003677 IEA DNA binding
GO:0003682 IDA chromatin binding
GO:0003684 IDA damaged DNA binding
GO:0003690 IDA double-stranded DNA binding
GO:0003725 IDA double-stranded RNA binding
GO:0003824 IEA catalytic activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005654 IDA nucleoplasm
GO:0005730 IDA nucleolus
GO:0005737 IEA cytoplasm
GO:0006266 IEA DNA ligation
GO:0006281 IEA DNA repair
GO:0006302 IDA double-strand break repair
GO:0006974 IMP cellular response to DNA damage stimulus
GO:0008219 IEA cell death
GO:0008967 IDA phosphoglycolate phosphatase activity
GO:0016311 IDA dephosphorylation
GO:0031647 IMP regulation of protein stability
GO:0033699 IEA:IDA DNA 5'-adenosine monophosphate hydrolase activity
GO:0042542 IDA response to hydrogen peroxide
GO:0046403 IDA polynucleotide 3'-phosphatase activity
GO:0046872 IEA metal ion binding
GO:0047485 IPI protein N-terminus binding
GO:0051219 IPI phosphoprotein binding
GO:0098506 IDA polynucleotide 3' dephosphorylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000027143 aptx aprataxin protein_coding Danio_rerio
ENSMUSG00000028411 Aptx aprataxin protein_coding Mus_musculus

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