C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000028479 Gne 10090 - 4:44034075-44084177 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000030201 Gne-001 44034075-44084177 protein_coding
  ENSMUST00000102936 Gne-002 44036826-44072778 protein_coding
  ENSMUST00000128439 Gne-004 44060103-44073017 protein_coding
  ENSMUST00000133709 Gne-006 44045955-44072624 nonsense_mediated_decay
  ENSMUST00000140724 Gne-005 44060112-44073018 protein_coding
  ENSMUST00000144985 Gne-003 44059868-44083923 protein_coding
  ENSMUST00000172514 Gne-014 44059700-44084167 retained_intron
  ENSMUST00000172533 Gne-008 44036830-44066920 nonsense_mediated_decay
  ENSMUST00000173234 Gne-009 44036958-44066960 protein_coding
  ENSMUST00000173274 Gne-011 44052875-44067061 protein_coding
  ENSMUST00000173383 Gne-010 44059991-44072602 protein_coding
  ENSMUST00000173569 Gne-012 44059972-44072736 processed_transcript
  ENSMUST00000173976 Gne-013 44055305-44063173 retained_intron
  ENSMUST00000174522 Gne-007 44036810-44055297 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000030201ENSMUST00000102936ENSMUST00000140724ENSMUST00000172533ENSMUST00000173234ENSMUST00000173274ENSMUST00000173569ENSMUST00000174522
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000030201 2.762±0.00 1.077±0.20 2.234±0.26 3.019±0.92 1.705±0.23 31.394±5.20 N/A 1.531±0.46 2.060±0.79 2.665±0.18 0.405±0.00 1.863±0.40 2.336±0.75 0.157±0.00
ENSMUST00000102936 3.538±0.35 2.032±0.40 2.861±0.41 3.993±3.09 2.245±0.79 13.917±0.00 0.680±0.00 2.620±0.39 5.064±1.06 4.408±0.28 0.838±0.23 3.437±1.40 9.133±5.05 0.378±0.20
ENSMUST00000140724 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 37.889±0.00 N/A
ENSMUST00000172533 N/A N/A N/A N/A 2.917±0.00 29.450±5.08 0.740±0.00 N/A 5.018±1.69 N/A N/A 1.808±0.08 3.118±0.00 0.229±0.00
ENSMUST00000173234 3.510±1.44 2.711±0.33 N/A N/A 3.326±0.28 58.275±12.11 1.444±0.34 3.250±0.59 10.842±2.10 4.992±0.38 0.421±0.00 4.220±1.08 2.060±0.00 0.291±0.02
ENSMUST00000173274 N/A N/A N/A N/A 3.280±0.00 N/A 2.513±0.28 N/A 6.003±2.24 N/A 0.944±0.00 5.852±0.52 12.053±3.89 0.834±0.00
ENSMUST00000173569 N/A 5.202±1.90 N/A N/A 3.034±0.00 N/A N/A N/A N/A N/A N/A 4.658±1.31 N/A N/A
ENSMUST00000174522 N/A 2.723±0.00 N/A N/A N/A 27.817±3.80 N/A 2.524±0.00 6.854±1.19 N/A 0.676±0.15 3.599±1.38 14.142±3.58 0.392±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006K3 CIL_0006K3_0002 CGP 4:44004452-44084177
CIL_0006K4 CIL_0006K4_0002 CGP 4:44034075-44233789

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003824 ISS catalytic activity
GO:0004553 IEA hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005737 IEA cytoplasm
GO:0005829 IEA cytosol
GO:0006045 IEA N-acetylglucosamine biosynthetic process
GO:0006047 IEA UDP-N-acetylglucosamine metabolic process
GO:0006054 TAS N-acetylneuraminate metabolic process
GO:0008761 IEA UDP-N-acetylglucosamine 2-epimerase activity
GO:0009384 IEA N-acylmannosamine kinase activity
GO:0046835 IEA carbohydrate phosphorylation
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000037634 gne glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase protein_coding Danio_rerio
ENSG00000159921 GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase protein_coding Homo_sapiens

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